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Table 3 Comparative analysis of 28-day outcome in patients with sepsis (n(%))

From: Bisphosphoglycerate mutase predicts myocardial dysfunction and adverse outcome in sepsis: an observational cohort study

Baseline Parameters

28-day outcome

P value

Survival n = 61

28-day death n = 24

Gender

 Male

41 (67.2)

14 (58.3)

0.460

 Female

20 (32.8)

10 (41.7)

 

Age, years

65 (26)

74 (18)

0.013

APACHE II, score

22 (7)

34 (7)

< 0.001

SOFA, score

4 (2)

7 (3)

0.636

BPGM, ng/ml

 Negative

45 (73.8)

5 (20.8)

< 0.001

 Positive

16 (26.2)

19 (79.2)

 

Lactate, mmol/l

3.2 (2.1)

3.6 (2.8)

0.136

PCT, ng/ml

20.8(55)

43(81)

0.064

LDH, IU/l

328 (455)

461 (555)

0.133

AG, mmol/l

17.6 (7.6)

19.9 (10.1)

0.488

CK, IU/l

185 (403)

149 (859)

0.938

CK-MB, ng/ml

24 (31)

27 (32)

0.522

NT-proBNP, pg/ml

3456 (4059)

4810 (7442)

0.084

cTnI, ng/ml

0.038(0.19)

0.529 (1.92)

< 0.001

LVEF-S,%

52 (6)

36 (8)

< 0.001

Tei Index

0.38 (0.15)

0.65 (0.05)

< 0.001

  1. Data are presented as a number (%) or median with interquartile ranges. Bold values indicate P < 0.05 by Mann–Whitney U test (quantitative data), chi-square (categorical variables) method
  2. APACHE II Acute Physiology and Chronic Health Evaluation II score, SOFA Sequential Organ Failure Assessment, BPGM bisphosphoglycerate mutase, PCT procalcitonin, LDH Lactate dehydrogenase, AG Anion gap, CK Creatine kinase, CK-MB Creatine kinase-MB, NT-proBNP N-terminal-probrain natriuretic peptide, cTnI cardiac troponin I, LVEF-S left ventricular ejection fraction-simpson, Tei Index myocardial performance index, IQR interquartile range