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Table 1 Baseline clinical biochemical characteristics (n(%)/M(IQR))

From: Bisphosphoglycerate mutase predicts myocardial dysfunction and adverse outcome in sepsis: an observational cohort study

Baseline Parameters

Expression of serum BPGM

P value

Negative n = 50

Positive n = 35

Gender

 Male

33 (66.0)

22 (62.9)

0.765

 Female

17 (34.0)

13 (37.1)

 

Age, years

68 (20)

64 (24)

0.951

APACHE II, score

23 (9)

27 (12)

0.022

SOFA, score

7 (2)

7 (2)

0.924

Comorbidities

 Diabetes Mellitus

16 (32.0)

11 (31.4)

0.956

 Immunosuppression

0 (0.0)

1 (2.9)

0.412

 IHD

0 (0.0)

2 (1.2)

0.167

 Hypertension

25 (50.0)

14 (40.0)

0.363

 COPD

2 (4.0)

2 (5.7)

0.713

 CKD

4 (8.0%)

4 (11.4)

0.824

Lactate, mmol/l

3.2 (2.0)

3.4 (3.5)

0.165

PCT, ng/ml

27.6(59.7)

28(89.0)

0.422

LDH, IU/l

341 (472)

358 (466)

0.432

AG, mmol/l

18 (8)

17.8 (10)

0.782

CK, IU/l

203 (338.5)

134 (862)

0.486

CK-MB, ng/ml

25 (28)

26 (33)

0.652

NT-proBNP, pg/ml

3440 (4156)

4834 (5419)

0.114

cTnI, ng/ml

0.04 (0.30)

0.18 (0.98)

0.033

LVEF-S,%

50 (6.0)

45 (13)

0.001

Tei Index

0.39 (0.17)

0.62 (0.24)

0.001

  1. Data are presented as a number (%) or median with interquartile ranges. Bold values indicate P < 0.05 by Mann–Whitney U test (quantitative data), chi-square (categorical variables) method
  2. BPGM bisphosphoglycerate mutase, APACHE II Acute Physiology and Chronic Health Evaluation II score, SOFA Sequential Organ Failure Assessment, IHD ischemic heart disease, COPD chronic pulmonary disease, CKD chronic kidney disease, cTnI cardiac troponin I, PCT procalcitonin, LDH Lactate dehydrogenase, AG, Anion gap, CK Creatine kinase, CK-MB Creatine kinase-MB, NT-proBNP N-terminal-probrain natriuretic peptide, LVEF-S left ventricular ejection fraction-simpson, Tei Index myocardial performance index, IQR interquartile range
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BMC Infectious Diseases

ISSN: 1471-2334

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