Table 2 Baseline characteristics of patients with HFMD on admission

Demographics

 Male/female

21/19

26/22

35/19

82/60

 Median age (months)

(range)

16 (2.4–43.2)

25.6 (6.8–154.8)

19 (4.1–118.2)

21.7 (2.4–154.8)

 HCM city origin

18 (45)

19 (39.6)

23 (42.6)

60 (42.3)

 Other provinces

22 (55)

29 (60.4)

31 (57.4)

82 (57.7)

 Length of stay (days) Median (range)

3 (2–10)

4 (2–10)

7 (1–43)

5 (1–43)

Clinical features (n, %)

 Skin lesion

37 (92.5)

45 (93.8)

54 (100)

135 (95.1)

 Mouth ulcer

38 (95)

45 (93.8)

46 (85.2)

129 (90.8)

 High fever

25 (62.5)

36 (75)

50 (92.6)

111 (78.2)

 Cough

4 (10)

2 (4.1)

6 (11.1)

12 (8.5)

 Runny nose

13 (32.5)

1 (2.1)

3 (5.5)

17 (12)

 Vomiting

11 (27.5)

11 (22.9)

8 (14.8)

30 (21.1)

 Diarrhea

4 (10)

6 (12.5)

8 (14.8)

18)12.7)

 Lethargy

9 (22.5)

34 (70.8)

41 (75.9)

84 (59.2)

 Irritable

35 (87.5)

39 (81.3)

38 (70.4)

111 (78.2)

 Myoclonus (history)

8 (20)

35 (72.9)

33 (61.1)

75 (52.8)

 Sweating

2 (5)

1 (2.1)

5 (9.2)

8 (5.6)

 Drowsiness

1 (2.5)

3 (6.3)

10 (18.5)

14 (9.9)

 Trembling

0

18 (37.5)

16 (29.6)

34 (23.9)

 Mottled skin

0

2 (4.1)

5 (9.2)

7 (4.9)

 Pulse (beats/minute)

Median (range)

140 (110–168)

140 (106–187)

148 (118–190)

143.5 (106–190)

 SBP (mmHg)

Median (range)

92.5 (80–110)

100 (90–160)

105 (85–160)

100 (80–160)

 DBP (mmHg)

Median (range)

60 (45–68)

60 (50–95)

60 (52–100)

60 (45–100)

 Respiratory rate (breaths/minute)

Median( range)

32 (22–60)

34 (22–46)

38 (22–70)

34 (22–70)

Pathogens (n, %)

 EV-A71

12 (30)

31 (64.6)

37 (68.5)

80 (56.3)

 CVA6

2 (5)

2 (4.3)

1 (1.8)

5 (3.5)

 CVA10

6 (15)

0

0

6 (4.2)

 CV-A16

2 (5)

3 (6.4)

2 (3.6)

7 (4.9)

 Other enterovirus serotypes^a

8 (20)

4 (8.3)

8 (14.8)

20 (14.1)

 PCR negative

10 (25)

7 (14.6)

7 (13)

24 (16.9)