Skip to main content

Table 4 TBM risk score table for screening, derived from the simplified prevalence model

From: A novel diagnostic model for tuberculous meningitis using Bayesian latent class analysis

Criterion

50% CrI

Value

Score

HIV

1.03—1.53

Positive

2.5

TB-suggestive symptoms

1.56—1.89

Present

3.5

Cranial nerve palsy

0.53—0.98

Present

1.5

Past noticed TB contact

1.89—3.63

Present

5.0

GCS

0.17—0.23

3–6

2.0

7–8

3.0

9–12

4.0

13–15

5.0

Pulmonary TB/X-ray

0.90—1.58

Detected

2.5

Miliary TB/X-ray

0.49—1.52

Detected

2.0

Symptom duration  (days)

0.27—0.39

1

0.0

2–4

2.0

5–7

3.0

8–14

4.0

15–21

5.0

21 + 

6.0

Headache

0.62—1.10

Present

1.5

Fever

1.07—1.85

Present

2.5

Neck stiffness

0.26—0.57

Present

1.0

Psychosis

-1.47—-0.93

Present

-2.5

  1. TBM suspected: Total score >  = 14
  2. To simplify to calculation, the estimates were doubled before choosing the scores. The decision threshold was decided by the cutpoint in the total score that maximises Youden’s Index
  3. Continuous features were cut into bins so that each bin accounts for 1 incremental points