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Table 4 Patient characteristics at hospital admission for all patients and according to vital status at one-year follow-up

From: Baseline NT-proBNP levels as a predictor of short-and long-term prognosis in COVID-19 patients: a prospective observational study

 

All Patients (n 499)

Alive (n 407)

Dead (n 92)

 

n (%)

n (%)

n (%)

p*

Cardiovascular risk factors

Male sex

259 (51.9)

216 (53.1)

43 (46.7)

0.253

Age, yrs – median (IQR)

66.0 [52.0–77.0]

61.5 [50.0–73.0]

82.0 [75.0–88.0]

< 0.001

BMI, kg/m2 – median (IQR)

28.7 [25.6–32.8]

28.7 [25.3–32.5]

28.7 [26.2–33.7]

0.562

Ever smoked

107 (21.4)

86 (21.1)

21 (22.8)

0.773

Hypertension

245 (49.1)

179 (43.9)

66 (71.7)

< 0.001

Dyslipidemia

171 (34.3)

127 (31.2)

44 (47.8)

0.004

Diabetes mellitus

103 (20.6)

70 (17.2)

33 (35.9)

< 0.001

Comorbidities

Cerebrovascular disease

32 (6.4)

18 (4.4)

14 (15.2)

< 0.001

Coronary heart disease

36 (7.2)

20 (4.94)

16 (17.4)

)

< 0.001

Atrial fibrillation

38 (7.6)

20 (4.9)

18 (19.5)

< 0.001

Chronic heart failure

26 (5.2)

12 (2.9)

14 (15.2)

< 0.001

Chronic kidney disease

48 (9.6)

24 (5.9)

24 (26.1)

< 0.001

Cancer

67 (13.4)

48 (11.8)

19 (20.7)

0.035

Peripheral vascular disease

15 (3.0)

10 (2.5)

5 (5.4)

0.171

COPD

39 (7.8)

27 (6.6)

12 (13.0)

0.065

Laboratory blood tests – median [IQR]

Leukocytes, µL×10^3

6.50 [4.98–8.44]

6.36 [4.90–8.05]

8.00 [5.23–10.4]

0.001

Lymphocytes, µL×10^3

1.06 [0.74–1.50]

1.12 [0.81–1.55]

0.76 [0.50–1.20]

< 0.001

Creatinine, mg/dL

0.90 [0.71–1.12]

0.87 [0.68–1.06]

1.09 [0.86–1.60]

< 0.001

Haemoglobin, g/dL

13.6 [12.3–14.6]

13.8 [12.6–14.7]

12.8 [11.2–14.0]

< 0.001

LDH, U/L

287 [233–378]

281 [229–359]

380 [258–461]

< 0.001

C-reactive protein, mg/dL

7.8 [3.18–14.2]

6.70 [2.90–12.6]

11.7 [5.20–22.8]

< 0.001

D-Dimer, ng/mL

700 [440–1232]

640 [420–1065]

1020 [690–2480]

< 0.001

hs-cTnT, ng/L

0.00 [0.00-19.6]

0.00 [0.00–14.0]

31.0 [17.1–64.6]

< 0.001

NT-proBNP. pg/mL

164 [42.7–514]

109 [32.2–336]

1264 [367–4717]

< 0.001

  1. IQR, interquartile range; BMI, body mass index; COPD, chronic obstructive pulmonary disease; LDH, lactate dehydrogenase; hs-cTnT, high sensitive cardiac-specific troponin T
  2. *p-value for the comparison between alive vs. dead patients at one year