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Fig. 7 | BMC Infectious Diseases

Fig. 7

From: Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected

Fig. 7

Analysis of selected Gene Ontology (GO) terms. A Heatmap showing the top 10 differentially expressed genes (DEGs) (based on FDR) enriched in humoral responses, cytokine signaling, TNF production and T cell activation GO terms. The genes (rows) are grouped by the clinical phenotype: A = Asymptomatic, U = Uninfected, FU = Febrile malaria ensuing from Uninfected, FA = Febrile malaria ensuing from Asymptomatic. B Boxplots showing the normalized expression levels of selected DEGs per GO term. The boxplots are labelled based on the clinical phenotype: A = Asymptomatic, U = Uninfected, FU = Febrile malaria ensuing from U and FA = febrile malaria ensuing from A. Pairwise statistical analyses indicated in the plots are Wilcoxon tests corrected for multiple testing (Benjamini & Hochberg, * =  < 0.05, ** =  < 0.01 and *** =  < 0.001)

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BMC Infectious Diseases

ISSN: 1471-2334

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