Variables | Survival group (n = 95) | Death group (n = 73) | P |
---|---|---|---|
SaO2 (95 ~ 98%) | 96 (94 ~ 98.4) | 91 (85 ~ 96) | 0.027 |
PaO2 (83 ~ 108 mmHg) | 81 (70.5 ~ 101) | 67 (55.8 ~ 95.3) | 0.003 |
Lactic acid (0.36 ~ 1.25 mmol/L) | 1.5 (1 ~ 1.8) | 1.8 (1.1 ~ 2.5) | 0.014 |
WBC count (3.5 ~ 9.5 × 109/L) | 6.9 (4.6 ~ 10.0) | 8.4 (5.3 ~ 12.3) | 0.068 |
Neutrophil count (1.8 ~ 6.3 × 109/L) | 4.7 (2.9 ~ 8.3) | 7.9 (4.4 ~ 11.9) | 0.002 |
Lymphocyte count (1.1 ~ 3.2 × 109/L) | 0.9 (0.5 ~ 1.2) | 0.6 (0.4 ~ 0.9) | 0.009 |
Lymphocyte count < 1.0 × 109/L, n (%) | 56 (59.0) | 58 (79.45) | 0.005 |
NLR (0.78 ~ 3.53) | 5.9 (2.8 ~ 14.6) | 10.4 (5.7 ~ 27.0) | 0.001 |
Hemoglobin (130 ~ 175 g/L) | 117 (101 ~ 132.8) | 126 (103 ~ 139) | 0.179 |
Platelet count (125 ~ 350 × 109/L) | 188.5 (152.3 ~ 247.8) | 160 (134 ~ 197) | 0.004 |
CRP (0 ~ 10 mg/L) | 45.7 (11.0 ~ 85.7) | 60.5 (27.9 ~ 17.0) | 0.018 |
Albumin (40 ~ 55 g/L) | 34 (31.4 ~ 38.2) | 33.9 (31 ~ 37.1) | 0.672 |
ALT (9 ~ 50 U/L) | 26 (14 ~ 35) | 28 (19 ~ 43) | 0.111 |
AST (15 ~ 40 U/L) | 27.5 (18.3 ~ 41.8) | 41 (26 ~ 64) | < 0.001 |
ALP (45 ~ 125 U/L) | 66 (55.5 ~ 86) | 73 (59 ~ 108) | 0.073 |
Bilirubin (0 ~ 23 mmol/L) | 10.3 (7.2 ~ 13.9) | 11.8 (8.3 ~ 17.9) | 0.234 |
Potassium (3.5 ~ 5.3 mmol/L) | 4.0 (3.6 ~ 4.4) | 4.03 (3.6 ~ 4.7) | 0.421 |
Sodium (137 ~ 147 mmol/L) | 138.5 (135 ~ 141.6) | 139 (135.4 ~ 142.1) | 0.429 |
Urea (3.6 ~ 9.5 mmol/L) | 6.4 (5.1 ~ 11.2) | 10 (6.5 ~ 14.5) | 0.001 |
Creatinine (57 ~ 111 µmol/L) | 77.5 (54.5 ~ 112.3) | 96 (70 ~ 133) | 0.005 |
LDH (120 ~ 250 U/L) | 295 (227.5 ~ 355.5) | 432.5 (313.5 ~ 503) | < 0.001 |
D-dimer (0 ~ 0.55 mg/L) | 1.2 (0.7 ~ 3.7) | 2.2 (0.7 ~ 9.2) | 0.039 |
PT(9 ~ 13 s) | 12.3 (11.6 ~ 13.3) | 12.4 (11.4 ~ 13.5) | 0.962 |
Fibrinogen (2 ~ 4 g/dL) | 4.4 (3.4 ~ 5.5) | 4.6 (3.3 ~ 5.8) | 0.691 |
APTT (25 ~ 31.3 s) | 30.6 (27 ~ 33.4) | 31 (27.6 ~ 33.6) | 0.334 |
PCT (< 0.05 ng/mL) | 0.11 (0.06 ~ 0.6) | 0.47 (0.15 ~ 1.43) | 0.006 |
CKMB (0 ~ 5 ng/mL) | 1 (0.3 ~ 1.8) | 1.6 (0.8 ~ 3.6) | 0.001 |
Ultratroponin I (0 ~ 0.04 ng/mL) | 0.03 (0.01 ~ 0.07) | 0.06 (0.02 ~ 0.18) | 0.009 |
MYO (0 ~ 110 ug/ml) | 86.4 (56.5 ~ 166.1) | 166.7 (94.1 ~ 435.6) | < 0.001 |
NT-proBNP (0 ~ 125 pg/mL) | 462 (199.5 ~ 1345) | 755 (277 ~ 2439.5) | 0.032 |
IL-2 (≤ 11.4 pg/mL) | 2.6 (2.3 ~ 3.05) | 2.6 (2.4 ~ 3.4) | 0.636 |
IL-4 (≤ 12.9 pg/mL) | 4.9 (4.6 ~ 5.2) | 4.8 (4.6 ~ 5.1) | 0.333 |
IL-6 (≤ 20.0 pg/mL) | 32 (11 ~ 56.8) | 47.3 (22.4 ~ 243.1) | 0.007 |
IL-10 (≤ 5.9 pg/mL) | 6.1 (4.7 ~ 8.5) | 10 (6.7 ~ 17.1) | < 0.001 |
TNF (≤ 5.5 pg/mL) | 3.4 (2.9 ~ 5.1) | 3.1 (2.7 ~ 4.0) | 0.187 |
Interferon-γ (≤ 17.3 pg/mL) | 3 (2.4 ~ 4.2) | 2.5 (2.2 ~ 3.9) | 0.049 |
IgG (8.6 ~ 17.4 g/L) | 11 (9.3 ~ 11.9) | 12.6 (9.2 ~ 15.3) | 0.050 |
IgM (0.3 ~ 2.2 g/L) | 0.8 (0.6 ~ 1) | 0.7 (0.6 ~ 1.1) | 0.965 |
IgA (1 ~ 4.2 g/L) | 2.3 (1.8 ~ 2.6) | 1.8 (1.4 ~ 2.5) | 0.197 |
IgE (0 ~ 100 g/L) | 81.4 (18.4 ~ 183) | 92.7 (18.4 ~ 176) | 0.775 |
C3 (0.7 ~ 1.4 g/L) | 0.7 (0.5 ~ 0.9) | 0.7 (0.5 ~ 0.9) | 0.561 |
C4 (0.1 ~ 0.4 g/L) | 0.2 (0.1 ~ 0.2) | 0.2 (0.1 ~ 0.2) | 0.916 |
CD3 (56 ~ 86%) | 67.6 (60.7 ~ 73.9) | 58.1 (42.3 ~ 65.2) | < 0.001 |
CD3 count (723 ~ 2737 pcs/uL) | 450.5 (282.3 ~ 724.5) | 201 (123 ~ 275) | < 0.001 |
CD4(33 ~ 58%) | 36.9 (32.8 ~ 45.9) | 29.1 (21.5 ~ 40.5) | 0.002 |
CD4 count (404 ~ 1612 pcs/uL) | 254 (149.8 ~ 421.5) | 109 (52.5 ~ 175.3) | < 0.001 |
CD8 (19 ~ 38%) | 21.6 (16.7 ~ 33.5) | 19.6 (13.8 ~ 29.7) | 0.146 |
CD8 count (220 ~ 1129 pcs/uL) | 145.5 (97.5 ~ 277.8) | 72.5 (41.3 ~ 109.8) | < 0.001 |
CD19(5 ~ 22%) | 12.1 (7.1 ~ 17.5) | 22.2 (10.6 ~ 32.3) | 0.003 |
CD19 count (80 ~ 616 pcs/uL) | 79 (36.3 ~ 165) | 69 (34.8 ~ 123.8) | 0.645 |
CD16 + 56 (5 ~ 26%) | 15.8 (11.8 ~ 20.6) | 17.8 (7.8 ~ 27.6) | 0.806 |
CD16 + 56 count (84 ~ 724 pcs/uL) | 119 (57.8 ~ 184.5) | 49.5 (27.5 ~ 105.5) | 0.002 |