Table 1 Comparison of demographic, comorbidity, and clinical characteristics of CAPA group and non-fungal infection group
Variables | CAPA (n = 168) | Non-fungal infection (n = 168) | P |
|---|---|---|---|
Male, n (%) | 124 (73.8) | 118 (70.2) | 0.544 |
Age, years | 74.5 (62.0 ~ 83.0) | 71.0 (59.0 ~ 82.0) | 0.367 |
Smoking history, n (%) | 40 (23.8) | 20 (11.9) | 0.007 |
History of alcohol consumption, n (%) | 20 (11.9) | 17 (10.1) | 0.728 |
Comorbidity, n (%) | |||
Hypertension | 91 (54.2) | 79 (47.0) | 0.230 |
Diabetes | 46 (27.4) | 39 (23.2) | 0.452 |
Coronary artery disease | 42 (25.0) | 22 (13.1) | 0.008 |
Chronic obstructive pulmonary disease | 22 (13.1) | 9 (5.4) | 0.022 |
Cerebrovascular disease | 24 (14.3) | 19 (11.3) | 0.514 |
Malignancy | 30 (17.9) | 20 (11.9) | 0.167 |
Chronic renal insufficiency | 21 (12.5) | 10 (6.0) | 0.058 |
HIV infection | 2 (1.2) | 0 (0) | 0.499 |
Immunocompromised status | 32 (19.0) | 24 (14.3) | 0.306 |
First symptoms | |||
Fever (temperature ≥ 37.0℃), n (%) | 147 (87.5) | 133 (79.2) | 0.056 |
Maximum temperature, ℃, median (IOR) | 38.8 (38.2 ~ 39.5) | 38.9 (38.0 ~ 39.2) | 0.178 |
Cough, n (%) | 135 (80.4) | 145 (86.3) | 0.187 |
Expectoration, n (%) | 119 (70.8) | 118 (70.2) | 1.000 |
Chest tightness, n (%) | 69 (41.1) | 51 (30.4) | 0.053 |
Shortness of breath, n (%) | 80 (47.6) | 38 (22.6) | < 0.001 |
Fatigue, n (%) | 91 (54.2) | 69 (41.1) | 0.022 |
Myalgia, n (%) | 5 (3.0) | 28 (16.7) | < 0.001 |
Nasal congestion, runny nose, n (%) | 12 (7.14) | 10 (6.0) | 0.826 |
Nausea, vomiting, n (%) | 13 (7.7) | 14 (8.3) | 1.000 |
Abdominal pain, diarrhea, n (%) | 19 (11.3) | 12 (7.1) | 0.258 |
Vital signs on admission | |||
Systolic blood pressure, mmHg | 128.9 ± 22.6 | 128.4 ± 18.5 | 0.826 |
Diastolic blood pressure, mmHg | 74.1 ± 12.7 | 73.7 ± 10.6 | 0.768 |
Heart rate, beats/min | 88.6 ± 19.1 | 87.6 ± 17.2 | 0.593 |
Respiratory rate, breaths/min | 20.0 (18.0 ~ 22.0) | 20.0 (19.0 ~ 20.0) | 0.806 |
Body temperature, ℃ | 36.5 (36.3 ~ 36.8) | 36.5 (36.3 ~ 36.8) | 0.771 |
Severity of illness at admission, n (%) | |||
Mild and moderate | 111 (66.1) | 120 (71.4) | 0.346 |
Severe and critical | 57 (33.9) | 48 (28.6) | |
Severity of illness at worst, n (%) | |||
Mild and moderate | 30 (17.9) | 97 (57.7) | < 0.001 |
Severe and critical | 138 (82.1) | 71 (42.3) | |