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Table 6 Cox Proportional Hazard Model Predicting ICU Mortality

From: The prognostic importance of the pan-immune-inflammation value in patients with septic shock

Covariate (ref.)

Univariate

Multivariatea

HR (95% CI)

p

HR (95% CI)

p

Age ≥ 65 (< 65)

1.83 (0.88 – 3.80)

0.107

0.61 (0.24 – 1.56)

0.298

Male (Female)

1.39 (0.68 – 2.86)

0.365

  

BMI < 30 (≥ 30)

1.63 (0.69 – 3.84)

0.265

  

Diagnosis (Other)

 

0.449

  

 Malignity

1.32 (0.41 – 4.31)

0.642

  

 Respiratory

1.92 (0.86 – 4.29)

0.110

  

 Operational

0.01 (0.01 – 520.16)

0.968

  

Comorbidity absence (presence)

1.38 (0.65 – 2.94)

0.405

  

HT presence (absence)

0.96 (0.48 – 1.94)

0.914

  

DM presence (absence)

1.07 (0.46 – 2.52)

0.873

  

CV presence (absence)

1.01 (0.44 – 2.31)

0.981

  

High PIV (Low PIV)

2.13 (1.03 – 4.38)

0.041

1.77 (0.73 – 4.26)

0.204

Low GCS (High GCS)

3.31 (1.34 – 8.15)

0.009

2.18 (0.78 – 6.10)

0.136

High SOFA (Low SOFA)

9.41 (2.86 – 30.95)

 < 0.001

4.85 (1.22 – 19.32)

0.025

High APACHE II (Low APACHE II)

3.08 (1.47 – 6.45)

0.003

0.86 (0.33 – 2.28)

0.762

High Lactate mmol/L (Low Lactate)

6.56 (2.73 – 15.75)

 < 0.001

7.97 (2.19 – 29.08)

0.002

High CRP mg/L (Low CRP)

1.49 (0.72 – 3.08)

0.278

  

High PCT µg/L (Low PRT)

2.73 (1.11 – 6.69)

0.029

0.41 (0.12 – 1.42)

0.160

  1. HR Hazard Ratio
  2. aProportional Hazards assumption tested with Schoenfeld residuals (p > 0,05 satisfied for each parameter)