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Table 4 The diagnosis efficiency of PCT and CRP (GN group versus GP group)

From: Procalcitonin and C-reactive protein as diagnostic biomarkers in COVID-19 and Non-COVID-19 sepsis patients: a comparative study

Item

PCT

CRP

Optimal cutoff

1.03 ng/mL

34.02 mg/L

AUC (95% CI)

0.689 (0.591–0.786)

0.611 (0.505–0.717)

Standard error

0.050

0.054

Sensitivity, % (95% CI)

75.00 (63.91–83.56)

42.86 (30.02–56.73)

Specificity, % (95% CI)

61.22 (47.25–73.57)

81.94 (71.52–89.13)

Diagnostic accuracy, % (95% CI)

69.42(57.16–79.51)

58.69 (46.83–69.85)

Positive predictive value, % (95% CI)

73.97 (64.03–82.29)

77.71 (60.77–88.46)

Negative predictive value, % (95% CI)

62.50 (47.12–75.28)

49.39 (41.02–58.37)

Positive likelihood ratio, (95% CI)

1.93 (1.21–3.16)

2.37 (1.05–5.22)

Negative likelihood ratio, (95% CI)

0.41 (0.22–0.76)

0.70(0.49–0.98)

Diagnostic odds ratio, (95% CI)

4.73 (1.59–14.14)

3.40 (1.08–10.75)

Youden’s index (%)

36.22

24.80

P value

< 0.001

0.039

  1. AUC, area under the receiver operating characteristic. CI, confidence interval. PCT, procalcitonin. CRP, C-reactive protein