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Table 2 Incidences of residual respiratory symptoms (primary outcome) and long COVID-19 (secondary outcome)

From: Effects of antivirals on patients with COVID-19 breakthrough

 

n

Primary outcome

 

Secondary outcome

 

Event

n (%)

 

Person-days1

Event

n (%)

Unadjusted rate2

(95% CI)

Adjusted rate2,3

(95% CI)

SoC

68

19 (27.9)

 

2777

8 (11.8)

28.8 (12.4–56.8)

30.0 (14.6–61.6)

SoC + antiviral

74

15 (20.3)

 

2756

6 (8.1)

21.8 (8.0–47.4)

21.0 (9.1–48.3)

 Favipiravir

5

0 (0.0)

 

69

1

144.9 (3.7–807.5)

300.0 (142.4–631.8)

 Molnupiravir

68

14 (20.6)

 

2603

5

19.2 (6.2–44.8)

18.6 (1.7–198.2)

 Remdesivir

1

1 (100.0)

 

84

0

  1. Abbreviation: CI: confidence interval; SoC: standard of care.
  2. 1Outcome follow-up was available from January 1, 2021, to March 31, 2022.
  3. 2Rates are per 10,000 person-days.
  4. 3Poisson regression was used to adjust for gender, age, weight, height, vaccination status, comorbidities, and concurrent medications.