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Table 1 Baseline characteristics

From: Effects of antivirals on patients with COVID-19 breakthrough

 

SoC + antiviral

(n = 74)

SoC

(n = 68)

Overall

(n = 142)

Male gender

34 (45.9)

24 (35.3)

58 (40.8)

Age (years)

37.3 ± 9.6

35.0 ± 9.9

36.2 ± 9.8

 < 65

71 (95.9)

68 (100.0)

97.9

 ≥ 65

3 (4.1)

0 (0.0)

3 (2.1)

Weight (kg)

62.3 ± 13.1

58.6 ± 11.8

60.5 ± 12.6

Height (cm)

161.3 ± 7.7

160.0 ± 8.4

160.7 ± 8.0

Educational status

   

 Tertiary and above

69 (93.2)

59 (86.8)

128 (90.1)

 Secondary and below

5 (6.8)

9 (13.2)

14 (9.1)

Comorbidities

   

 Endocrine diseases1

3 (4.1)

3 (4.4)

6 (4.2)

 Cardiovascular diseases2

8 (10.8)

6 (8.8)

14 (9.9)

 Respiratory diseases3

2 (2.7)

5 (7.4)

7 (4.9)

 Gastrointestinal diseases4

3 (4.1)

0 (0.0)

3 (2.1)

 Musculoskeletal disorders5

3 (4.1)

0 (0.0)

3 (2.1)

 Cancers

0 (0.0)

3 (4.4)

3 (2.1)

First vaccine jab

   

 AZD12226

70 (94.6)

59 (86.8)

129 (90.8)

 mRNA-12737

1 (1.4)

1 (1.5)

2 (1.4)

 BNT162b28

2 (2.7)

2 (2.9)

4 (2.8)

 BBIBP-CorV9

1 (1.4)

6 (8.8)

7 (4.9)

Second vaccine jab

   

 AZD12226

69 (93.2)

59 (86.8)

128 (90.1)

 mRNA-12737

1 (1.4)

1 (1.5)

2 (1.4)

 BNT162b28

3 (4.1)

5 (7.4)

8 (5.6)

 BBIBP-CorV9

1 (1.4)

3 (4.4)

4 (2.8)

Concurrent medications

   

 Corticosteroids10

16 (21.6)

12 (17.6)

28 (19.7)

 Anticoagulants11

2 (2.7)

1 (1.5)

3 (2.1)

 Antipyretic agents12

62 (83.8)

42 (61.8)

104 (73.2)

 Antibiotics13

19 (25.7)

9 (13.2)

28 (19.7)

 Herbal medications14

10 (13.5)

15 (22.1)

25 (17.6)

  1. Abbreviation: SoC: standard of care.
  2. 1Diabetes (type 2), hypothyroidism, hyperthyroidism.
  3. 2Hypertension, heart failure, coronary artery diseases, tachycardia, congenital heart diseases.
  4. 3Asthma, chronic obstructive pulmonary disease, allergic rhinitis, rhinosinusitis.
  5. 4Peptic ulcer, cirrhosis.
  6. 5Gout, osteoarthritis, osteoporosis.
  7. 6AstraZeneca vaccine.
  8. 7Moderna vaccine.
  9. 8Pfizer/BioNTech vaccine.
  10. 9Sinopharm vaccine.
  11. 10Prednisone, prednisolone, methylprednisolone, dexamethasone.
  12. 11Rivaroxaban, dabigatran.
  13. 12Paracetamol (acetaminophen), ibuprofen.
  14. 13Amoxicillin, amoxicillin-clavulanate, azithromycin, clarithromycin.
  15. Note: All variables were reported with frequency (percentage), except for age, weight, and height, which were presented as mean ± standard deviation.