Table 5 AUCs of cytokines in each antigen tube for distinguishing ATB from LTBI
Parameter | TNF-α | IL-6 | IP-10 | MCP-1 | IFN-γ | IL-1Ra | IL-2 | CXCL-1 |
|---|---|---|---|---|---|---|---|---|
TB1-Nil | ||||||||
AUC (95%CI) | 0.780 (0.605–0.955) | 0.843 (0.707–0.980) | 0.850 (0.704–0.996) | 0.667 (0.487–0.847) | 0.793 (0.641–0.946) | 0.723 (0.551–0.896) | 0.477 (0.282–0.671) | 0.767 (0.594–0.940) |
p | 0.005 | 0.001 | < 0.001 | 0.096 | 0.003 | 0.026 | 0.816 | 0.008 |
TB2-Nil | ||||||||
AUC (95%CI) | 0.780 (0.622–0.938) | 0.817 (0.679–0.955) | 0.920 (0.808-1.000) | 0.650 (0.463–0.837) | 0.773 (0.616–0.931) | 0.763 (0.599–0.927) | 0.433 (0.242–0.625) | 0.778 (0.611–0.945) |
p | 0.005 | 0.002 | < 0.001 | 0.134 | 0.006 | 0.008 | 0.505 | 0.005 |
TB2-TB1 | ||||||||
AUC (95%CI) | 0.475 (0.278–0.672) | 0.403 (0.210–0.597) | 0.693 (0.520–0.867) | 0.380 (0.187–0.573) | 0.527 (0.328–0.726) | 0.600 (0.410–0.790) | 0.363 (0.177–0.549) | 0.517 (0.319–0.714) |
p | 0.803 | 0.334 | 0.053 | 0.230 | 0.790 | 0.317 | 0.172 | 0.868 |