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Table 4 AUCs of cytokines in each antigen tube for diagnosing ATB

From: Multiple cytokine analysis based on QuantiFERON-TB gold plus in different tuberculosis infection status: an exploratory study

Parameter

TNF-α

IL-6

IP-10

MCP-1

IFN-γ

IL-1Ra

IL-2

CXCL-1

TB1-Nil

AUC (95%CI)

0.78

(0.66–0.90)

0.819

(0.709–0.928)

0.897

(0.802–0.992)

0.760

(0.631–0.889)

0.879

(0.792–0.965)

0.807

(0.693–0.921)

0.623

(0.456–0.790)

0.840

(0.72–0.96)

p

0.001

< 0.001

< 0.001

0.001

< 0.001

< 0.001

0.132

< 0.001

TB2-Nil

AUC (95%CI)

0.801

(0. 687-0.916)

0.829

(0.723–0.934)

0.94

(0.873-1.000)

0.75

(0.62–0.88)

0.823

(0.712–0.933)

0.821

(0.711–0.932)

0.592

(0.423–0.761)

0.848

(0.731–0.965)

p

< 0.001

< 0.001

< 0.001

0.002

< 0.001

< 0.001

0.259

< 0.001

TB2-TB1

AUC (95%CI)

0. 481

(0.300-0.663)

0.443

(0.274–0.612)

0.699

(0.546–0.851)

0.409

(0.236–0.581)

0.500

(0.322–0.678)

0.621

(0.453–0.790)

0.419

(0.230–0.607)

0.509

(0.321–0.698)

p

0.820

0.484

0.015

0.263

1.000

0.137

0.319

0.909

  1. AUC, area under the curve; CI, confidence interval