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Fig. 2 | BMC Infectious Diseases

Fig. 2

From: Hsa-miR-194-5p and hsa-miR-195-5p are down-regulated expressed in high dysplasia HPV-positive Pap smear samples compared to normal cytology HPV-positive Pap smear samples

Fig. 2

Heatmap representing differently expressed miRNAs against substantially enriched functional networks. a Hierarchical clustering results for each miRNAs and their relevant pathways are shown. Hippo signaling pathway and adherens junction pathway were overlapped pathways between candidate miRNAs. The figure depicted is based on the online output of Diana miRpath V.2 using the algorithm of miRTarBase v7.0. b Predicted pathways heat map DIANA-microT-CDS (v5.0) algorithm. Based on this algorithm, the wnt signaling pathway and signaling pathways regulating the pluripotency of stem cells were common among candidate miRNAs. Lower P values (more significant) and higher interplay of each miRNA with a particular molecular pathway are indicated by reddish color combinations in the heatmap

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BMC Infectious Diseases

ISSN: 1471-2334

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