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Table 3 Demographic characteristics and outcomes in SARS-CoV2 PCR-positive hospitalized patients based on cycle threshold (Ct) range

From: Characteristics, outcome, duration of hospitalization, and cycle threshold of patients with COVID-19 referred to four hospitals in Babol City: a multicenter retrospective observational study on the fourth, fifth, and sixth waves

Characteristic

Total

Ct value range

p-value

9 - 20

21 - 30

31 - 40

Overall

6379

1695

3879

805

–

Median age, yrs., (IQR)

54 (26)

55 (27)

53 (25)

54 (25)

0.066

Mean ± SD age, yrs

52.93 ± 18.81

53.03 ± 20.5

52.9 ± 17.9

52.6 ± 19.6

0.744

Age group, yrs

  < 18

245 (3.8)

101 (6)

101 (2.6)

43 (5.3)

< 0.001

 18–49

2363 (37.1)

560 (33.1)

1531 (39.5)

272 (23.8)

 50–64

2003 (31.4)

528 (31.2)

1208 (31.2)

267 (33.2)

 65-79

1277 (20)

346 (20.4)

774 (20)

157 (19.5)

  ≥ 80

487 (7.6)

159 (9.4)

262 (6.8)

66 (8.2)

Sexa

 Men

2769 (43.8)

734 (43.3)

1681 (43.3)

381 (47.3)

0.101

 Women

3583 (56.2)

961 (56.7)

2198 (56.7)

424 (52.7)

Underlying diseases

 CVD

1162 (18.2)

313 (18.5)

685 (17.7)

164 (20.4)

0.183

 Diabetics

1032 (16.2)

287 (16.9)

600 (15.5)

145 (18)

0.126

 Kidney diseases

135 (2.1)

51 (3)

68 (1.8)

16 (2)

0.011

 Hypertension

524 (8.2)

119 (7)

337 (8.7)

68 (8.4)

0.11

 Malignancies

135 (2.1)

39 (2.3)

75 (1.9)

21 (2.6)

0.397

 RD

146 (2.3)

39 (2.3)

88 (2.3)

19 (2.4)

0.987

 Liver diseases

33 (0.5)

8 (0.5)

23 (0.6)

2 (0.2)

0.443

 GID

4 (0.06)

1 (0.06)

3 (0.1)

0 (0.0)

0.726

 BND

240 (3.4)

72 (4.2)

140 (3.6)

28 (3.5)

0.464

 BD

24 (0.4)

7 (0.4)

15 (0.4)

2 (0.2)

0.809

 Pregnancy

94 (1.5)

38 (2.2)

47 (1.2)

9 (1.1)

0.009

 Others

47 (0.7)

11 (0.6)

27 (0.7)

9 (1.1)

0.393

Comorbidities

 No-Comorbidities

3834 (60.1)

983 (58)

2394 (61.7)

457 (56.8)

0.009

 One

1701 (26.7)

492 (29)

977 (25.2)

232 (28.8)

  ≥ Two

844 (13.2)

220 (13)

508 (13.1)

116 (14.4)

Hospitalization outcome

 Length of stay, days, median (IQR)

5 (3)

5 (3)

5 (3)

5 (3)

0.054

 Length of stay, days, Mean ± SD

6.7 ± 8.1

6.8 ± 7.01

6.60 ± 7.85

6.69 ± 11.39

0.054

 ICU admission

289 (4.5)

90 (5.3)

175 (4.5)

24 (3)

0.33

 Death

235 (307)

103 (6.1)

103 (2.7)

29 (3.6)

< 0.001

SARS-CoV-2 epidemic waves and variant predominance status

 Waves 0

633 (9.9)

106 (6.3)

427 (11)

100 (12.4)

< 0.001

 4th (alpha) wave

1355 (21.2)

444 (26.2)

742 (19.1)

169 (21)

 5th (delta) wave

3554 (55.7)

919 (54.2)

2207 (56.9)

428 (53.2)

 6th (omicron) wave

836 (13.1)

226 (13.3)

502 (12.9)

108 (13.4)

  1. 1) Wave 0: related to between waves of SARS-CoV-2 Infections; 2) CVD: Cardiovascular Diseases; 3) KD: Kidney Diseases; 4) RD: Respiratory Disorders; 5) GID: Gastrointestinal Diseases; 6) BND) Brain & Neurologic Diseases; 7) BD: Blood Disorders; 8) Others including: Special diseases, Thyroiditis, Lupus and Immunodeficiency diseases
  2. a27 cases were missing