Table 6 Extracted data, sensitivity and specificity estimates in the systematic review of studies evaluating the diagnostic accuracy of PCR and IgM ELISA, published global and between 1950 – 2022
Study first author, ref | Reference test | Total N samples | Index + /Reference +  | Index + /Reference- | Index-/Reference +  | Index-/Reference- | Sensitivity | Specificity |
|---|---|---|---|---|---|---|---|---|
A. PCR studies | ||||||||
 Merien F [27] | MAT | 51 | 10 | 15 | 1 | 25 | 92% (72–100) | 66% (49–91) |
 Esteves L [40] | PCR | 202 | 46 | 0 | 1 | 155 | 98% (90–100) | 99% (98–100) |
B. IgM ELISA studies | ||||||||
 Bourhy P [41] | MAT | 519 | 298 | 3 | 19 | 199 | 97% (93–100%) | 99% (97–100%) |