Associations of MMP9 polymorphism with the risk of severe pneumonia in a Southern Chinese children population

BMC Infectious Diseases

Table 4 Risk allele frequency of MMP9 gene SNPs between severe pneumonia subgroups

CHR	BP	SNP	Major allele	Minor allele	Minor Allele Frequency in primary pneumonia	Minor Allele Frequency in secondary pneumonia	OR (95% CI)	P
20	44643770	rs3918262	A	G	0.440	0.484	0.846 (0.699–1.026)	0.0888
20	44643111	rs17577	G	A	0.120	0.010	1.212 (0.889–1.654)	0.2231
20	44638781	rs3918251	G	A	0.270	0.250	1.118 (0.888–1.409)	0.3420
20	44642406	rs2250889	C	G	0.196	0.181	1.110 (0.865–1.426)	0.4114
20	44640391	rs3918254	C	T	0.222	0.209	1.074 (0.846–1.363)	0.5565
20	44645153	rs9509	T	C	0.233	0.229	1.020 (0.812–1.282)	0.8628

The P-values were corrected by Bonferroni’s method with a threshold of 0.0042. Calculation of the OR was also based on the minor allele of each SNP
Abbreviations: CHR Chromosome, BP Base pair (where the SNP is located), SNP Single-nucleotide polymorphism, OR Odds ratio, CI Confidence interval, P P-value adjusted by gender and age

ISSN: 1471-2334