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Table 2 Factors that impact the serum level of IgG-S1 antibodies against SARs-CoV-2 in samples of individuals after recovering from the first infection of COVID-19

From: A stronger antibody response in increased disease severity of SARS-CoV-2

Variables

IgG Antibody

p-value

Median (Q1; Q3)

Hospitalization

 Yes

6.76 (4.98; 8.14)

 < 0.001*

 No

2.67 (1.18; 4.74)

 

Sex

 Male

4.95 (1.73; 7.33)

0.033*

 Female

3.70 (1.90; 6.07)

 

Obesity

 Yes

4.96 (2.49; 6.81)

0.014*

 No

3.62 (1.47; 6.78)

 

Symptoms at diagnosis

 1–3

3.92 (1.32; 6.70)

0.026**

 4–5

5.02 (2.67; 7.38)

 

  ≥ 6

4.16 (1.82; 6.31)

 

Age (in years)

 18 to 45

2.20 (1.01; 4.08)

 < 0.001**

 46 to 59

5.33 (2.60; 6.98)

 

 60 or over

5.65 (3.19; 7.45)

 

SAH

 Yes

5.85 (3.26; 7.42)

 < 0.001*

 No

3.27 (1.42; 5.83)

 

T2DM

 Yes

5.97 (3.94; 7.64)

 < 0.001*

 No

3.81 (1.58; 6.29)

 

IgG antibody titers in DASO

 Up to 90 DASO

6.20 (3.43; 8.08)

 < 0.001**

 91 to 180 DASO

3.82 (2.05; 6.10)

 

  > 180 DASO

2.63 (1.25; 5.01)

 
  1. (*) Mann–Whitney (**) Kruskal–Wallis
  2. SAH denotes Systemic arterial hypertension, T2DM Type 2 diabetes mellitus, DASO Days after symptom onset, IgG-S Anti-spike Immunoglulin G
  3. This tables show the results of Mann-Withney and Kruskal–Wallis to indicate the impact of each variable separately on the serum level IgG-S1 antibodies against SARs-CoV-2