From: A stronger antibody response in increased disease severity of SARS-CoV-2
Variables | Hospitalization | ||||
---|---|---|---|---|---|
Yes | No | OR | CI 95% OR | p-value | |
n = 87 (%) | n = 151(%) | ||||
Sex | |||||
Male | 57 (65.5%) | 73 (48.3%) | 2.03 | 1.18 – 3.50 | 0.010 * |
Female | 30 (34.5%) | 78 (51.7%) | 1.00 | –- | |
Ages (in years) | |||||
18 to 45 | 14 (16.1%) | 67 (44.4%) | 1.00 | –- | < 0.001* |
46 to 59 | 37 (42.5%) | 65 (43.0%) | 2.72 | 1.35 – 5.50 | |
≥ 60 | 36 (41.1%) | 19 (12.6%) | 9.07 | 4.07 – 20.19 | |
Symptoms | |||||
Fever | 61 (70.1%) | 74 (50.0%) | 2.35 | 1.34 – 4.11 | 0.003* |
Cough | 64 (73.6%) | 72 (48.6%) | 2.94 | 1.65 – 5.22 | < 0.001* |
Dyspnea | 74 (85.1%) | 46 (31.1%) | 12.62 | 6.37 – 25.03 | < 0.001* |
No change in sense of smell | 48 (55.2%) | 49 (33.1%) | 2.49 | 1.14 – 4.28 | < 0.001* |
Myalgia | 40 (46.0%) | 74 (50.0%) | 0.85 | 0.50 – 1.45 | 0.551* |
Asthenia | 45 (51.7%) | 84 (56.8%) | 0.82 | 0.48 – 1.39 | 0.454* |
Sore throat | 11 (12.6%) | 51 (34.5%) | 0.28 | 0.13 – 0.56 | < 0.001* |
Diarrhea | 18 (20.7%) | 46 (31.1%) | 0.58 | 0.31 – 1.08 | 0.084* |
Abdominal pains | 10 (11.5%) | 19 (12.8%) | 0.88 | 0.39 – 1.99 | 0.762* |
Headache | 28 (32.2%) | 100 (67.6%) | 0.23 | 0.13 – 0.40 | < 0.001* |
No symptoms | 0 (0.0) | 11 (7.3%) | –- | –- | –- |
Comorbidities | |||||
SAH | 59 (67.8%) | 35 (23.8%) | 6.74 | 3.74 – 12.15 | < 0.001* |
T2DM | 33 (37.9%) | 13 (8.8%) | 6.30 | 3.08 – 12.88 | < 0.001* |
Obesity | 38 (46.3%) | 50 (36.2%) | 1.52 | 0.87 – 2.64 | 0.139* |
Oxygen therapy | |||||
Non-invasive | 69 (79.3%) | –- | –- | –- | –- |
Invasive mechanical ventilation | 18 (20.7%) | –- | –- | –- | –- |
Time in ICU | 29 (33.3%) | –- | –- | –- | –- |
Distribution of samples | |||||
Up to 90 DASO | 72 (48.6%) | 75 (34.1%) | –- | –- | 0.003* |
91 to 180 DASO | 41 (27.7%) | 58 (26.4%) | –- | –- | - |
> 180 DASO | 35 (23.6%) | 87 (39.5%) | –- | –- | - |
Presence of IgG-S antibody | |||||
Positive | 145 (98.0%) | 168 (76.4%) | 11.22 | 3.40 – 37.07 | < 0.001* |
Negative | 3 (2.0%) | 39 (17.7%) | 1.00 | –- | |
Undetermined | 0 (0.0) | 13 (5.9%) | ** | ** |