Table 2 Evolution of patients with COVID-19 in the Adult Intensive Care Units of the Hospital de Clínicas between August 2020 and August 2021. San Lorenzo. Paraguay (n = 214)
Variable | Remdesivir n = 109 | No Remdesivir n = 105 | OR (CI 95%) | P |
|---|---|---|---|---|
Length of stay in the ICU, median (IQR) | 11 (11) | 10 (10) | - | 0.150 |
SaO2/FIO2, median (IQR) | 160 (63) | 146 (73) | - | 0.353 |
PaO2 /FIO2, median (IQR) | 102 (77) | 100 (63) | - | 0.671 |
MV at admission, n (%) | 40 (36,7) | 61 (58,1) | 0.4182 (0.2414–0.7244) | 0.001 |
NIMV at admission, n (%) | 1 (0,9) | 4 (3,8) | 0.2338 (0.026–2.1271) | 0.1730 |
MV total, n (%) | 59 (54.1) | 76 (72.4) | 0.450 (0,255-0,796) | 0.006 |
Days of MV, median (IQR) | 13.5 (13) | 11 (11) | - | 0.039 |
ARDS, n (%) | 43 (43.9) | 68 (60.0) | 0.521 (0.302-0.900) | 0.019 |
Prone position, n (%) | 56 (57.7) | 71 (61.2) | 0.866 (0.500-1.499) | 0.607 |
Norepinephrine, n (%) | 51 (52.0) | 73 (62.9) | 0.639 (0.370–1.104) | 0.108 |
Hemodialysis, n (%) | 13 (13.3) | 11 (9.5) | 0.460 (0.623–3.424) | 0.382 |
Kidney injury | 23/93 (24.7) | 41/96 (42.7) | 0.441 (0.237–0.820) | 0.009 |
Hepatic injury | 9/47 (19.1) | 5/57 (8.8) | 2.463 (0.764–7.940) | 0.123 |
Intercurrent infection, n (%) | 70 (71.4) | 95 (81.9) | 0.553 (0.290–1.053) | 0.069 |
Death, n (%) | 29 (26.6) | 53 (50.5) | 0.356 (0.201–0.630) | < 0.001 |