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Table 3 Risk Factors for clinical and microbiological outcomes in pediatric MRSA bacteremia

From: The molecular epidemiology and clinical implication of methicillin-resistant Staphylococcus aureus (MRSA) sequence types in pediatric bacteremia: a restrospective observational study, 2016–2021

 

30-day all-cause mortality (n = 8)

Persistent bacteremia at day 7 (n = 9)

n (%)

OR (95% CI)

aOR (95% CI)

n (%)

OR (95% CI)

aOR (95% CI)

Age (years)

-

0.96 (0.82–1.13)

NA

-

1.067 (0.95–1.2)

NA

Hospital onset

7 (87.5)

3.06 (0.35–26.48)

NA

8 (88.9)

3.73 (0.44–31.8)

NA

Primary source of infection

      

 None

3 (37.5)

2.85 (0.60–13.57)

4.51 (0.71–28.73)

0 (0.0)

NA

NA

 CVC infection

3 (37.5)

0.55 (0.12–2.48)

NA

5 (55.6)

1.18 (0.29–4.77)

NA

 Pneumonia

1 (12.5)

1.83 (0.19–17.96)

NA

3 (33.3)

10.5 (1.73–63.91)

8.63 (1.25–56.62)

 BJI & SSTI

0 (0.0)

NA

NA

0 (0.0)

NA

NA

 SSI

1 (12.5)

3.14 (0.29–34.42)

NA

1 (11.1)

2.63 (0.24–28.36)

NA

 IE

0 (0.0)

NA

NA

0 (0.0)

NA

NA

Severe presentation

1 (12.5)

0.68 (0.08–6.04)

NA

2 (22.2)

1.429(0.26–7.82)

NA

Vancomycin MIC = 2 (µg/mL)

1 (12.5)

1.83 (0.19–17.96)

NA

1 (11.1)

1.525(0.16–14.76)

NA

ST groups

      

 ST1 group a

3 (37.5)

39.0 (3.40–444.06)

44.12 (3.46–562.19)

2 (22.2)

17.71 (1.42–221.15)

14.37 (0.96–216.06)

 ST5 group b

0 (0.0)

NA

NA

1 (11.1)

0.48 (0.06–4.20)

NA

 ST72 group c

5 (62.5)

0.78 (0.17–3.56)

NA

5 (55.6)

0.54 (0.13–2.23)

NA

  1. Abbreviations: OR, odds ratio; aOR, adjusted odds ratio; CI, confidence interval; CVC, central venous catheter; BJI, bone and joint infection; SSTI, skin and soft tissue infection; IE, infective endocarditis; MIC, minimal inhibitory concentration; ST sequence type; NA, not applicable; SLV, single locus variant
  2. Notes: a ST1 (n = 3) and its SLVs, including novel SLV (n = 1)
  3. b ST5 (n = 9) and its SLVs including ST632(n = 1), novel SLV(n = 4).
  4. c ST72 (n = 47) and its SLVs including ST2084(n = 2), novel SLV(n = 1).