Table 4 Relationship between drugs and outcomes of patients’ in subgroup
Variables | Patients older than 80 years | Patients younger than 79 years | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
All cohort (N = 848) | Non-ACEI group (N = 441) | ACEI group (N = 407) | OR/β(95%CI) | P value | All cohort (N = 675) | Non-ACEI group (N = 322) | ACEI group (N = 353) | OR/β(95%CI) | P value | |
Exacerbation | 122(14.33) | 78(17.75) | 43(10.64) | 0.56(0.37–0.83) a | 0.0039 | 55(8.08) | 23(7.06) | 32(9.01) | 0.90(0.48–1.68) a | 0.7454 |
All-cause death | 40(4.71) | 28(6.36) | 12(2.93) | 0.45(0.23–0.90) a | 0.0235 | 8(1.26) | 4(1.34) | 4(1.18) | 0.89(0.23–3.45) a | 0.8634 |
Mechanical ventilation | 77(9.06) | 46(10.39) | 31(7.62) | 0.72(0.45–1.16) a | 0.1767 | 19(2.78) | 15(4.76) | 3(0.97) | 0.16(0.05–0.57) a | 0.0046 |
Respiratory failure | 86(10.11) | 55(12.42) | 31(7.62) | 0.59(0.37–0.94) a | 0.0252 | 19(2.78) | 15(4.76) | 3(0.97) | 0.16(0.05–0.57) a | 0.0046 |
Nucleic acid conversion time (NCT) days | 15.00(11.00–19.00) | 16.00(11.00–20.00) | 14.00(10.00–18.00) | -1.34(-2.68-0.01) b | 0.0513 | 12.00(9.00–16.00) | 12.00(9.00–18.00) | 12.00(9.00–16.00) | -0.93(-2.3-0.45) b | 0.1861 |
Total hospitalization costs, dollars | 1595.64(1073.72-2673.14) | 1695.23(1075.64-2836.08) | 1546.37(1072.97-2514.90) | 34.50(-514.59-583.59) b | 0.9018 | 1175.18(859.81-1753.43) | 1207.48(889.06-1837.47) | 1142.40(851.43-1664.66) | -269.05(-639.62-101.51) b | 0.1541 |