Table 1 Information regarding the conserved domains of the 14 putative immunogenic proteins against C. burnetii was gathered from the NCBI Conserved Domain Database (CDD), EggNOG, and STRING databases
UniProt ID (Locus_tag) | CDD | EggNOG | STRING |
|---|---|---|---|
Q83F57 (CBU_0092) | Periplasmic TolA-binding protein (CpoB) | Function unknown (protein trimerization) | Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division. |
Cell cycle control, cell division, chromosome partitioning (Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division) | |||
Q83EW1 (CBU_0197) | Hypothetical outer membrane protein | Cell wall/membrane/envelope biogenesis | Hypothetical outer membrane protein |
Function unknown | |||
Q83EK8 (CBU_0311) | Outer membrane porin P1 | omp1 | Outer membrane protein P1 |
Cell wall/membrane/envelope biogenesis (Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety) | |||
Q83E43 (CBU_0489) | Phospholipase A1 | Cell wall/membrane/envelope biogenesis (1-acyl-2-lysophosphatidylserine acylhydrolase activity) | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. |
Phospholipase | |||
Q83DJ4 (CBU_0736) | Hypothetical protein (Unknown) | No orthologs found | Hypothetical exported protein |
Q83D08 (CBU_0939) | Uncharacterized protein involved in outer membrane biogenesis (ASMA) | Cell wall/membrane/envelope biogenesis (Protein involved in outer membrane biogenesis) | AsmA family |
AsmA family | |||
Q83CL9 (CBU_1095) | Hypothetical exported protein (Unknown) | No orthologs found | Hypothetical exported protein |
P39917 (CBU_1190) | Outer membrane lipoprotein carrier protein LolA; pfam03548 | Cell wall/membrane/envelope biogenesis (Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.) | Outer-membrane lipoproteins carrier protein (Participates in the translocation of lipoproteins from the inner membrane to the outer membrane). |
Q83BU0 (CBU_1412) | Hypothetical exported protein | Cell wall/membrane/envelope biogenesis (Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety) | Hypothetical exported protein. |
Q83BT8 (CBU_1414) | hypothetical exported protein (Legionella pneumophila major outer membrane protein precursor) | Cell wall/membrane/envelope biogenesis (Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety) | Hypothetical exported protein |
Q83BB2 (CBU_1600) | Heat resistant agglutinin | Cell wall/membrane/envelope biogenesis (Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety) | Uncharacterized protein |
Q83B86 (CBU_1627) | IcmE (T4SS_IcmE_DotG) | Function unknown (protein homooligomerization) | IcmE |
Intracellular trafficking, secretion, and vesicular transport (multi-organism process) | |||
Q83AQ2 (CBU_1829) | Outer membrane lipoprotein receptor (LolB) | Protein transport (lolB) | Outer-membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. |
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein | |||
Q83A32 (CBU_2079) | Hypothetical protein (Unknown) | No orthologs found | Uncharacterized protein |