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Table 3 Adjusteda hazard ratios and odds ratios for each outcome measure per decrease of 10 percentiles in rainfall versus historical values in an observational cohort study of the effect of rainfall on HIV outcomes in Southern Africa

From: Associations of inter-annual rainfall decreases with subsequent HIV outcomes for persons with HIV on antiretroviral therapy in Southern Africa: a collaborative analysis of cohort studies

  

Per 10 percentile decrease in rainfall

Mortality

N PWH (N with outcome)

Adjusted hazard ratios (95% confidence interval)

 Overall

104,138 (2951)

1.18 (1.07–1.32)

 Urban

75,061 (1899)

NAb

 Rural

29,077 (1052)

1.18 (1.06–1.32)

CD4 counts < 200 cells/mm3

N PWH (N with outcome)

Adjusted odds ratios (95% confidence interval)

 Overall

27,580 (3990)

0.94 (0.89–1.00)

 Urban

23,154 (3167)

0.94 (0.88–1.01)

 Rural

4426 (823)

0.99 (0.89–1.10)

HIV-1 viral loads > 400 copies/mL

N PWH (N with outcome)

Adjusted odds ratios (95% confidence interval)

 Overall

82,860 (13,788)

1.05 (1.01–1.09)

 Urban

77,519 (13,341)

1.05 (1.01–1.09)

 Rural

4741 (447)

Did not converge

 ≥ 12-month gaps in care

N PWH (N with outcome)

Adjusted hazard ratios (95% confidence interval)

 Overall

270,708 (9426)

0.98 (0.94–1.01)

 Urban

222,865 (8015)

0.96 (0.92–1.00)

 Rural

47,843 (1411)

0.86 (0.80–0.93)

  1. aAdjusted for cohort, male/female sex at birth, a binary variable to indicate locations with a Normalized Difference Vegetation Index (NDVI) value ≥ 0.3, and age, CD4 count cells/mm3, viral load copies/mL, AIDS status, and the time since starting ART time-updated at follow-up start
  2. bResult due to there being no within-cohort variation in rainfall
  3. PWH People with HIV