Fig. 2

Risk of bias analysis using (A) Cochrane Risk of Bias tool for randomised controlled trials and (B) ROBINS-1 tool for non-randomised clinical trials (including observational studies). Abbreviation: RCT- Randomised controlled trials, nRCTs- non-Randomised controlled trials, D- Domains of bias. *Colour grading- Red- High risk of bias, Yellow- Moderate risk of bias and Green- Low risk of bias. D1 to D7 stands for the various domains of critical appraisal