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Table 3 Bivariate analysis for sociodemographic and clinical characteristics of study participants on DTG-based ART in Mengo Hospital, Kampala, Uganda, 2022 (n = 341)

From: Dyslipidemia among adult people living with HIV on dolutegravir – based antiretroviral therapy at a private tertiary hospital in Kampala, Uganda: burden and determinants

Variable

Dyslipidemia

cPR

95% CI

P value

No

Yes

Sex

      
 

Male

48 (42.5)

65 (57.5)

Reference

  
 

Female

27 (11.8)

201 (88.2)

1.53

1.30–1.81

< 0.001

Age

25–49

51 (21.2)

190 (78.8)

Reference

  
 

18–24

1 (10.0)

9 (90.0)

1.14

0.92–1.42

0.232

 

≥ 50

23 (25.6)

67 (74.4)

0.94

0.82–1.08

0.415

Education level

Post primary

54 (26.0)

154 (74.0)

Reference

  
 

Primary or less

21 (15.8)

112 (84.2)

1.14

1.02–1.27

0.021

Physical activity

High

38 (23.3)

155 (76.7)

Reference

  
 

Low

37 (20.8)

141 (79.2)

0.56

0.92–1.16

0.306

Alcohol Use

No

55 (20.5)

`214 (79.5)

Reference

  
 

Yes

20 (27.8)

52 (72.2)

0.91

0.78–1.06

0.224

DTG duration (years)

≥ 2

62 (24.5)

191 (75.5)

Reference

  
 

< 2

13 (14.8)

75 (85.2)

1.13

1.01–1.26

0.034

ART duration (years)

< 10

49 (24.1)

154 (75.9)

Reference

  
 

≥ 10

26 (28.8)

112 (81.2)

1.07

0.96–1.20

0.237

HIV duration (years)

< 10

43 (24.2)

135 (75.8)

Reference

  
 

≥ 10

32 (19.6)

131 (80.4)

1.06

0.95–1.19

0.313

Baseline CD4* (n = 340)

< 200

30 (24.8)

91 (75.2)

Reference

  
 

200–499

≥ 500

30 (20.6)

15 (20.3)

116 (79.4)

59 (79.7)

1.08

0.90

0.92–1.25

072–1.12

0.347

0.311

Previous ART regimen

NNRTI based

65 (23.1)

217 (76.9)

Reference

  
 

PI based

2 (12.5)

14 (87.5)

1.14

0.93–1.38

0.199

 

None

8 (18.6)

35 (81.4)

1.06

0.90–1.24

0.483

BMI

normal

43 (29.7)

102 (70.3)

Reference

  
 

overweight

19 (20.2)

75 (79.8)

1.13

0.98–1.31

0.093

 

obese

13 (12.8)

89 (87.2)

1.24

1.09–1.41

0.001

FBG

Normal

72 (22.3)

251 (77.7)

Reference

  
 

High

3 (16.7)

15 (83.3)

1.07

0.86–1.33

0.524

  1. * Missing data, n- number of participants, CI - confidence interval, cPR -crude prevalence ratio, BMI – body mass index, DTG - dolutegravir, NNRTI – non-nucleoside reverse transcriptase inhibitor, PI – protease inhibitor, ART - antiretroviral therapy, FBG - fasting blood glucose