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Table 1 Comparison of baseline characteristics between patients with and without bacteremia

From: Clinical effects of bacteremia in sepsis patients with community-acquired pneumonia

 

Total

(n = 1,510)

Non-bacteremia

(n = 1,298)

Bacteremia

(n = 212)

p value

Age, years

74.0 (64.0–81.0)

74.0 (64.0–81.0)

73.0 (64.2–82.0)

0.683

Sex, male

1,039 (68.8)

897 (70.1)

142 (61.7)

0.013

Body mass index, kg/m2

21.0 (18.3–23.7)

20.9 (18.3–23.6)

21.3 (18.9–24.2)

0.180

Clinical frailty scale

5.0 (3.2–7.0)

5.0 (3.0–7.0)

6.0 (4.0–7.0)

0.026

History of antibioticsa

374 (24.7)

331 (25.5)

43 (20.3)

0.122

History of hospitalizationb

468 (30.9)

406 (31.0)

62 (29.3)

0.576

Comorbidity

 Diabetes mellitus

509 (33.7)

431 (33.2)

78 (36.8)

0.309

 Cardiovascular disease

404 (26.7)

346 (26.7)

58 (27.4)

0.867

 Chronic lung disease

438 (29.0)

397 (30.6)

41 (19.3)

< 0.001

 Chronic kidney diseasec

178 (11.7)

144 (11.1)

34 (16.0)

0.051

 Chronic neurological disease

318 (21.0)

269 (20.7)

49 (23.1)

0.415

 Connective tissue disease

39 (2.5)

32 (2.5)

7 (3.3%)

0.482

 Solid malignant tumor

500 (33.1)

442 (34.1)

58 (27.4)

0.066

 Hematologic malignancy

86 (5.7)

62 (4.8)

24 (11.3)

< 0.001

 Immunodeficiency

44 (2.9)

35 (2.7)

9 (4.3)

0.266

Charlson comorbidity index

5.0 (4.0–7.0)

5.0 (4.0–7.0)

5.0 (4.0–7.0)

0.812

Septic shock

250 (16.5)

192 (14.8)

58 (27.4)

< 0.001

SOFA score

5.0 (3.0–7.0)

5.0 (3.0–7.0)

7.0 (5.0–10.0)

< 0.001

Vital signs

 Mean blood pressure, mmHg

73.3 (63.3–93.3)

73.7 (64.0–94.0)

66.7 (60.0–81.0)

< 0.001

 Heart rate, /min

110.0 (94.0–126.0)

110.0 (94.0–125.0)

113.0 (98.0–130.0)

0.048

 Respiratory rate, /min

24.0 (22.0–28.0)

24.0 (22.0–28.0)

24.0 (22.0–30.0)

0.221

Laboratory findings

 White blood cell count,103/μL

11.0 (7.0–15.4)

11.1 (7.2–15.6)

10.4 (5.1–14.1)

0.008

 Hemoglobin, g/dL

11.3 (9.6–13.1)

11.4 (9.7–13.2)

10.6 (8.8–12.7)

< 0.001

 Platelets, × 103/μL

194 (124–273)

204.0 (135.0–278.7)

145.0 (77.5–241.5)

< 0.001

 ANC, × 103/μL

8.8 (5.3–12.9)

8.9 (5.5–13.2)

8.7 (3.5– 11.6)

0.023

 Creatinine, mg/dL

1.2 (0.8–1.9)

1.2 (0.8–1.8)

1.5 (1.0–2.5)

< 0.001

 Total bilirubin, mg/dL

0.7 (0.5–1.2)

0.7 (0.5–1.1)

1 (0.6–1.6)

< 0.001

 Prothrombin time, INR

1.1 (1.0– 1.3)

1.1 (1.0–1.3)

1.2 (1.1–1.4)

< 0.001

 Albumin, g/dL

3.1 (2.6–3.6)

3.2 (2.7–3.6)

2.8 (2.4–3.2)

< 0.001

 C-reactive protein, mg/dL

10.6 (4.5 –19.4)

9.9 (4.2–18.4)

15.7 (8.3–25.4)

< 0.001

 Procalcitonin, mmol/L

1.0 (0.2–6.4)

0.8 (0.2–4.6)

4.2 (1.0–24.1)

< 0.001

 Lactate, mmol/L

2.4 (1.5–4.5)

2.3 (1.4–4.0)

3.8 (2.0–6.2)

< 0.001

  1. Values are median (interquartile range, IQR) or number (%)
  2. ANC absolute neutrophil count, SOFA Sequential Organ Failure Assessment
  3. aHistory of antibiotic prescription within the past 30 days
  4. bHospitalization for ≥ 2 of the past 90 days
  5. cChronic kidney disease is defined as either kidney damage or GFR < 60 mL/min/1.73 m2 for 3 months
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BMC Infectious Diseases

ISSN: 1471-2334

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