Table 5 Univariate and multivariate analysis of covariates associated with target trough achievement

Sex

1.470

0.423–5.105

0.544

Age (years)

1.057

1.003–1.114

0.039*

1.152

0.997–1.331

0.054

Body weight (kg)

1.057

1.002–1.116

0.043*

0.929

0.804–1.073

0.315

Apache II score

1.016

0.863–1.198

0.846

SOFA score

1.006

0.809–1.250

0.959

Albumin (g/L)

1.007

0.925–1.097

0.864

Serum creatinine (μmol/L)

1.018

1.002–1.035

0.032*

1.018

0.993–1.045

0.158

Cys-C (mg/L)

5.249

1.972–13.972

0.001*

5.274

1.780–15.627

0.003*