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Table 4 Multivariate analysis of risk factors associated with Indeterminate QFT-GIT results in childhood tuberculosis

From: Interferon-gamma release assay for screening of tuberculosis infection in children

Variable

Indeterminate

(n = 2420)

Determinate

(n = 16,113)

Univariable analysis

 

Multivariate analysis

Crude OR (95% CI)

P value

 

Adjusted OR(95% CI)

P value

Gender

       

M

1382(57.1)

9103(56.5)

Reference

-

 

Reference

-

F

1038(42.9)

7010(43.5)

0.98(0.90–1.06)

0.57

 

0.97(0.95-1.00)

0.045

Age group, y

       

0–4

1340(55.4)

4699(29.2)

6.27(4.33–9.09)

<0.01

 

8.29(7.51–9.14)

<0.001

5–9

778(32.1)

5641(35.0)

3.03(2.09–4.41)

<0.01

 

3.32(3.01–3.67)

<0.001

10–14

272(11.2)

5113(31.7)

1.17(0.80–1.72)

0.42

 

1.16(1.05–1.29)

0.004

15–17

30(1.2)

660(4.1)

Reference

-

 

Reference

-

Diseases Classification

       

Respiratory

685(19.3)

2178(11.2)

4.96(4.26–5.79)

<0.01

 

3.64(3.32–4.01)

<0.001

Central nervous

114(3.2)

851(4.4)

2.11(1.68–2.67)

<0.01

 

1.60(1.44–1.78)

<0.001

Urinary

270(7.6)

1794(9.2)

2.38(1.98–2.84)

<0.01

 

2.84(2.66–3.02)

<0.001

Digestive

473(13.3)

2623(13.5)

2.85(2.43–3.34)

<0.01

 

2.86(2.72-3.00)

<0.001

Hematological and neoplastic

534(15.1)

3200(16.5)

2.63(2.25–3.08)

<0.01

 

2.07(1.99–2.17)

<0.001

Rheumatic immune

967(27.3)

3135(16.1)

4.87(4.21–5.63)

<0.01

 

5.20(5.00-5.41)

<0.001

Cardiovascular

248(7.0)

1656(8.5)

2.36(1.97–2.84)

<0.01

 

2.20(2.09–2.30)

<0.001

Other

254(7.2)

4009(20.6)

Reference

-

 

Reference

-