Table 3 Multivariate analysis of risk factors associated with Indeterminate X.DOT-TB results in childhood tuberculosis
From: Interferon-gamma release assay for screening of tuberculosis infection in children
Variable | Indeterminate (n = 626) | Determinate (n = 14,503) | Univariable analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|---|
Crude OR (95% CI) | P value | Adjusted OR (95% CI) | P value | ||||
Gender | |||||||
M | 390(62.3) | 8004(55.2) | Reference | - | Reference | - | |
F | 236(37.7) | 6499(44.8) | 0.75(0.63–0.88) | <0.01 | 0.71(0.66–0.76) | <0.001 | |
Age group, y | |||||||
0–4 | 281(44.8) | 4799(33.1) | 1.61(1.03–2.50) | 0.03 | 2.04(1.70–2.45) | <0.001 | |
5–9 | 195(31.2) | 4914(33.9) | 1.09(0.70–1.71) | 0.71 | 1.37(1.14–1.64) | 0.001 | |
10–14 | 128(20.4) | 4186(28.9) | 0.84(0.53–1.33) | 0.46 | 0.90(0.74–1.08) | 0.26 | |
15–17 | 22(3.5) | 604(4.2) | Reference | - | Reference | - | |
Diseases Classification | |||||||
Respiratory | 177(21.6) | 4282(24.1) | 1.10(0.87–1.39) | 0.43 | 0.91(0.77–1.07) | 0.25 | |
Central nervous | 40(4.9) | 741(4.2) | 1.44(1.00-2.07) | 0.05 | 1.19(0.94–1.50) | 0.15 | |
Urinary | 41(5.0) | 1075(6.1) | 1.01(0.71–1.45) | 0.94 | 1.05(0.87–1.23) | 0.61 | |
Digestive | 97(11.8) | 1573(8.9) | 1.64(1.25–2.15) | <0.01 | 1.61(1.43–1.82) | <0.001 | |
Hematological and neoplastic | 120(14.6) | 1438(8.1) | 2.22(1.71–2.87) | <0.01 | 1.97(1.78–2.19) | <0.001 | |
Rheumatic immune | 174(21.2) | 4259(24.0) | 1.09(0.86–1.37) | 0.49 | 1.16(1.06–1.27) | 0.001 | |
Cardiovascular | 47(5.7) | 1072(6.0) | 1.17(0.83–1.64) | 0.38 | 1.06(0.93–1.21) | 0.37 | |
Other | 124(15.1) | 3297(18.6) | Reference | - | Reference | - | |