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Table 1 Characteristics of COVID-19 confirmed cases by period regarding vaccination and circulating variants of SARS-CoV-2

From: Changes in the intrinsic severity of severe acute respiratory syndrome coronavirus 2 according to the emerging variant: a nationwide study from February 2020 to June 2022, including comparison with vaccinated populations

Class

Total

Pre-vaccination

After-vaccination

Pre- delta dominant

Delta dominant

Omicron dominant

Total

18,286,735

(100.0)

94,179

(100.0)

72,518

(100.0)

493,557

(100.0)

17,626,481

(100.0)

Sex

 Male

8,597,627

(47.0)

46,617

(49.5)

37,622

(51.9)

258,770

(52.4)

8,254,618

(46.8)

 Female

9,689,108

(53.0)

47,562

(50.5)

34,896

(48.1)

234,787

(47.6)

9,371,863

(53.2)

Age (years)

 Mean ± SD

37.3 ± 21.7

45.7 ± 20.6

41.5 ± 19.2

40.2 ± 21.7

37.1 ± 21.7

  0–9

2,184,409

(11.9)

3,894

(4.1)

3,712

(5.1)

45,512

(9.2)

2,131,291

(12.1)

  10–19

2,390,072

(13.1)

6,398

(6.8)

5,941

(8.2)

54,157

(11.0)

2,323,576

(13.2)

  20–29

2,667,693

(14.6)

14,191

(15.1)

12,362

(17.0)

71,844

(14.6)

2,569,296

(14.6)

  30–39

2,691,201

(14.7)

12,453

(13.2)

11,297

(15.6)

72,573

(14.7)

2,594,878

(14.7)

  40–49

2,823,960

(15.4)

13,572

(14.4)

12,467

(17.2)

70,814

(14.3)

2,727,107

(15.5)

  50–59

2,261,051

(12.4)

17,431

(18.5)

12,930

(17.8)

65,012

(13.2)

2,165,678

(12.3)

  60–69

1,855,102

(10.1)

14,642

(15.5)

8,979

(12.4)

69,436

(14.1)

1,762,045

(10.0)

  70–79

879,645

(4.8)

7,084

(7.5)

3,380

(4.7)

29,042

(5.9)

840,139

(4.8)

   ≥ 80

533,602

(2.9)

4,514

(4.8)

1,450

(2.0)

15,167

(3.1)

512,471

(2.9)

Vaccination

 None

4,124,629

(22.6)

94,178

(100.0)

70,160

(96.7)

246,166

(49.9)

3,714,125

(21.1)

 Partial

209,788

(1.1)

1

(0.0)*

1,990

(2.7)

39,389

(8.0)

168,408

(1.0)

 Complete

5,441,223

(29.8)

0

(0.0)

368

(0.5)

201,809

(40.9)

5,239,046

(29.7)

 Booster

8,511,095

(46.5)

0

(0.0)

0

(0.0)

6,193

(1.3)

8,504,902

(48.3)

Outcome

 Severe/criticala)

23,258

(0.1)

2,774

(2.9)

1447

(2.0)

8525

(1.7)

10,512

(0.1)

  Average per day

26.4

6.9

12.0

46.8

60.4

  Mean age (years± SD)

69.3 ± 15.5

71.1 ± 12.2

65.1 ± 14.1

65.4 ± 15.4

72.6 ± 15.7

   ≥ 60

18,170

(78.1)

2,354

(84.9)

987

(68.2)

5,898

(69.2)

8,931

(85.0)

   ≥ 80

6,560

(28.2)

703

(25.3)

225

(15.5)

1,583

(18.6)

4,049

(38.5)

Death

24,611

(0.1)

1,749

(1.9)

348

(0.5)

4,672

(0.9)

17,842

(0.1)

 Average per day

27.9

4.3

2.9

25.7

102.5

  Mean age (years± SD)

79.6 ± 12.1

79.3 ± 10.6

76.7 ± 12.1

77.0 ± 12.3

80.3 ± 12.1

   ≥ 60

23,063

(93.7)

1,665

(95.2)

318

(91.4)

4,303

(92.1)

16,777

(94.0)

   ≥ 80

14,492

(58.9)

964

(55.1)

159

(45.7)

2,226

(47.6)

11,143

(62.5)

  1. COVID-19 coronavirus disease, SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2, SD Standard deviation
  2. *< 0.1
  3. aSevere/critical case: Patients who were treated with non-invasive ventilation, high flow oxygenation, invasive ventilation, extracorporeal membrane oxygenation, or continuous renal replacement treatment during isolation from COVID-19