Fig. 7From: Humoral and T cell responses to SARS-CoV-2 reveal insights into immunity during the early pandemic period in PakistanT cell IFN-γ activation observed in response to SARS-CoV-2 Spike protein in COVID-19 cases, healthy individuals from the pandemic and pre-pandemic period. The presence of reactive T cells secreting IFN-γ to Spike S1 protein was determined by ELISpot analysis. PBMCS were plated on IFN-γ coated plates and stimulated with S1 protein for 18 h. The graph depicts the number of T cells secreting IFN-γ identified for COVID-19 (n = 18), HG (n = 6) and PP (n = 7) groupsBack to article page