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Fig. 4 | BMC Infectious Diseases

Fig. 4

From: Humoral and T cell responses to SARS-CoV-2 reveal insights into immunity during the early pandemic period in Pakistan

Fig. 4

Time-course analysis of IgG antibody levels to Spike and RBD in a Healthy Group. IgG antibodies in the healthy group (HG) were analysed in two-monthly intervals between October 2020 to May 2021. Antibody levels in participants are shown for Oct-Nov’20 (n = 66), Dec’20-Jan’21 (n = 65), Feb-Mar’21 (n = 155) and Apr-May’21 (n = 18). IgG levels to Spike (A) and RBD (B) are depicted. Data are shown as geometric means as horizontal line and 95%CI as error bars. The positive cut-off (0.5 OD) is shown by a dotted line. C The frequency of seropositive responses to Spike and RBD in each period is shown. Significant differences (p ≤ 0.05) calculated by MWU analysis

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