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Table 2 Patient characteristics

From: Clinical experience of treatment of immunocompromised individuals with persistent SARS-CoV-2 infection based on drug resistance mutations determined by genomic analysis: a descriptive study

No

Age

Sex

Comorbidities

Vaccination frequency

Initial spike-specific antibody (U/ml)

Viral load

Initial GA (copy/µL) (Days after onset)

Viral load

Subsequent GA (copy/µL) (Days after onset)

Current immunosuppressive drug

Severity of COVID-19

1

81

Female

DLBCL

3

61.9

387834 (2)

318187 (31)

218663 (51)

Rituximab

Obinutuzumab

Bendamustine

Severe

2

71

Male

Kidney transplantation

3

<0.4

1351495 (9)

1466 (24)

Tacrolimus

Mycophenolate mofetil

Methylprednisolone

Critical

3

66

Female

Kidney transplantation

3

 < 0.4

8570 (1)

7670 (21)

Tacrolimus

Mycophenolate mofetil

Methylprednisolone

Moderate

4

44

Male

Kidney transplantation

3

<0.4

135269 (2)

21798 (19)

Tacrolimus

Mycophenolate mofetil

Methylprednisolone

Moderate

5

80

Female

DLBCL

2

14.9

2839493 (0)

5853 (13)

2130 (28)

Polatuzumab vedotin

Rituximab

Bendamustine

Moderate

6

35

Female

Malignant lymphoma

none

20763

2420,183 (3)

627186 (10)

Unknown

Moderate

7

74

Male

Multiple myeloma

none

1.73

5425 (18)

708919 (32)

Pomalidomide

Bortezomib

Severe

8

78

Male

Follicular lymphoma

5

1740

34647 (0)

165652 (18)

Polatuzumab vedotin

Rituximab

Bendamustine

Critical

9

70

Female

Autoimmune hepatitis

none

 < 0.4

704487 (6)

54144 (29)

Rituximab

Prednisolone

Severe

10

80

Male

Multiple myeloma

4

 < 0.4

22116 (0)

2049 (33)

32566 (46)

Pomalidomide

Ixazomib

Severe

11

49

Female

Kidney transplantation

3

<0.4

5578198 (2)

842 (19)

Mycophenolate mofetil

Cyclosporine

Moderate

12

79

Female

Follicular lymphoma

3

8945

 

513 (90)

Rituximab

Obinutuzumab

Bendamustine

Severe

13

54

Male

Follicular lymphoma

3

<0.4

 

52051 (55)

Rituximab

Obinutuzumab

Bendamustine

Severe

14

81

Male

Follicular lymphoma

2

2814

 

537627 (74)

Rituximab

Obinutuzumab

Bendamustine

Severe

15

81

Male

MALT lymphoma

4

84.5

 

31406 (173)

Rituximab

Bendamustine

Critical

16

54

Female

Follicular lymphoma

none

2153

 

619 (125)

Obinutuzumab

Bendamustine

Severe

17

82

Male

Kidney transplantation

4

<0.4

 

16042 (17)

Tacrolimus

Mycophenolate mofetil

Prednisolone

Critical

  1. GA Genomic analysis, DLBCL Diffuse large B-cell lymphoma, MALT Mucosa-associated lymphoid tissue