Table 1 Details of patients starting treatment at our hospital (Nos. 1–11) and patients who were transferred after treatment at other hospitals (Nos. 12–17)
| Â | Â | Â | Mutations before the treatment for COVID-19 | Â | Mutations after the treatment for COVID-19 | Â | ||||
|---|---|---|---|---|---|---|---|---|---|---|
No | PANGOLIN | GISAID count | NSP5 (number of registrations) [% of mutation] | NSP12 (number of registrations) [% of mutation] | RBD (number of registrations) [% of mutation] | Drugs administered prior to subsequent GA | NSP5 (number of registrations) [% of mutation] | NSP12 (number of registrations) [% of mutation] | RBD (number of registrations) [% of mutation] | Outcome |
1 | BA.1.1 | 1047522 | – | – | – | Rem, Nir/Rit Sot | – | A625V(11)[50%] | *P337S(71)[54%] *E340K(228)[100%] F374L(11)[39%] | Ended isolation |
2 | BA.1.1 | 1047522 | – | – | – | Rem Sot | – | – | *S371F(1817)[78%] | Ended isolation |
3 | BA.1.1.2 | 62165 | – | – | – | Rem Sot | – | *C799F(3)[72%] | – | Ended isolation |
4 | BA.2.29 | 8463 | – | – | – | Mol Cas/Imd | – | – | – | Ended isolation |
5 | BA.5.1 | 254400 | – | – | – | Rem, Mol Nir/Rit Cas/Imd | Q273R(2)[45%] | R457C(12)[44%] | *K444R(638)[46%] *G446S(183)[23%] | Ended isolation |
6 | BA.5.1 | 254,400 | – | – | – | Mol Cas/Imd | – | I145V(5)[57%] D164N(0)[55%] | *G446S(183)[20%] *G446D(114)[34%] P499S(6)[59%] | Ended isolation |
7 | BA.5.2.1 | 302404 | – | – | – | Mol Cas/Imd | – | D260N(6)[99%] | V445A(1309)[91%] | Ended isolation |
8 | BA.5.2.1 | 302404 | – | – | – | Rem, Ens Tix/Cil (before onset) | *M49L(0)[100%] | A529V(1808)[100%] G671S(708)[35%] E796D(7)[64%] | *R346S(220)[33%] *N450D(994)[62%] | Ended isolation |
9 | BA.5.2.6 | 12935 | – | – | – | Mol, Rem Tix/Cil | – | – | – | Ended isolation |
10 | BA.5.2.46 | 155 | – | – | – | Ens, Mol | – | – | – | Ended isolation |
11 | BF.5 | 85649 | – | – | – | Mol Sot | – | – | – | Ended isolation |
12 | BA.1.1.1 | 66698 |  |  |  | Sot | – | P227S(8)[100%] | *P337H(9)[99%] *S371F(272)[99%] Y508H(1)[100%] | Ended isolation |
13 | BA.5.2.1 | 302404 |  |  |  | Rem, Mol | – | – | – | Ended isolation |
14 | BA.5.1 | 254400 |  |  |  | Rem, Nir/Rit Tix/Cil | K90R(1127)[96%] | T246I(749)[99%] *C799Y(6)[96%] | – | Ended isolation |
15 | BA.5.2.1 | 302404 | Â | Â | Â | Rem Cas/Imd | Q273R(1)[24%] | *V166A(8)[34%] E796K(5)[29%] | L368I(23)[24%] K417H(1)[19%] *G446S(227)[25%] | Ended isolation |
16 | BA.5.2.1 | 302404 | Â | Â | Â | Rem Tix/Cil | K236R(40)[99%] | V233I(36)[100%] G671S(708)[100%] P918L(143)[99%] | L335S(3)[98%] G339Y(46)[58%] *K444R(726)[96%] | Ended isolation |
17 | BF.5 | 85649 |  |  |  | Rem | – | E876D(0)[27%] | Y369H(0)[33%] V503F(0)[28%] | Death |