From: Diabetes mellitus and latent tuberculosis infection: an updated meta-analysis and systematic review
 | Studies (n) | Participants (n) | aOR (95% CI) | I2 (%) | pval* |
---|---|---|---|---|---|
Population | |||||
 Contacts | 5 | 7065 | 1.26 (1.07–1.50) | 28 | 0.866 |
 Immigrants or refugees | 3 | 5275 | 1.44 (1.01–2.06) | 69 | 0.861 |
 Immunosuppressed patients | 2 | 4858 | 0.84 (0.50–1.40) | 0 | 0.127 |
 Others | 3 | 5386 | 1.15 (1.00–1.34) | 0 | 0.400 |
 Community residents | 6 | 27,294 | 1.31 (0.09–1.58) | 52 | Ref |
Study region | |||||
 Europe | 3 | 14,273 | 1.15 (1.03–1.29) | 0 | 0.5702 |
 North America | 7 | 36,633 | 1.41 (1.11–1.77) | 57 | 0.4662 |
 Asia | 9 | 16,446 | 1.22 (1.11–1.34) | 17 | Ref |
DM diagnostics | |||||
 Self-report | 6 | 19,705 | 1.17 (1.06–1.28) | 0 | 0.0238 |
 Others | 8 | 37,664 | 1.21 (1.09–1.35) | 25 | 0.0456 |
 HbA1c | 5 | 9983 | 1.56 (1.24–1.96) | 41 | Ref |
LTBI diagnostics | |||||
 TST | 4 | 5666 | 1.17 (1.04–1.32) | 0 | 0.6171 |
 TST and/or IGRA | 4 | 30,201 | 1.39 (1.08–1.80) | 52 | 0.5118 |
 IGRA | 11 | 31,485 | 1.24 (1.10–1.40) | 40 | Ref |
LTBI prevalence | |||||
 ≥ 30% | 6 | 33,135 | 1.17 (1.06–1.28) | 0 | 0.2687 |
 < 30% | 13 | 34,217 | 1.31 (1.15–1.49) | 38 | Ref |
TB burdena | |||||
 0–30 per 100,000 | 9 | 50,520 | 1.26 (1.11–1.45) | 49 | 0.5536 |
 30–100 per 100,000 | 8 | 15,068 | 1.19 (1.06–1.34) | 0 | 0.4116 |
 > 100 per 100,000 | 2 | 1764 | 1.38 (0.98–1.95) | 65 | Ref |
Risk of bias | |||||
 Moderate | 3 | 8227 | 1.17 (1.01–1.37) | 19 | 0.6465 |
 Low | 16 | 59,125 | 1.24 (1.14–1.35) | 34 | Ref |