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Table 4 Univariate and multivariate Cox regression analysis of predictors of all-cause mortality in the overall and matched cohorts

From: Device-related infection and mortality in patients with chronic kidney disease receiving cardiac implantable electronic devices: a propensity score-matched cohort study

 

Overall cohorts

 

Matched cohorts

Univariate analysis

Multivariate analysis

 

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

 

HR (95% CI)

P value

HR (95% CI)

P value

Age, (years)

1.05 (1.04–1.06)

< 0.001

1.05 (1.03–1.06)

< 0.001

 

1.05 (1.03–1.07)

< 0.001

1.06 (1.04–1.08)

< 0.001

Male

1.05 (0.84–1.32)

0.678

   

1.12 (0.83–1.52)

0.451

  

Body mass index, (kg/m2)

0.94 (0.91–0.97)

< 0.001

0.96 (0.93–0.99)

0.006

 

0.93 (0.89–0.97)

< 0.001

0.98 (0.94–1.02)

0.235

Hypertension

1.07 (0.83–1.37)

0.612

   

0.67 (0.49–0.93)

0.016

0.66 (0.47–0.93)

0.017

Diabetes mellitus

1.70 (1.35–2.13))

< 0.001

1.21 (0.95–1.53)

0.128

 

1.22 (0.90–1.65)

0.206

  

Hyperlipidemia

0.86 (0.67–1.09)

0.198

   

0.76 (0.55–1.05)

0.092

0.77 (0.54–1.08)

0.132

Coronary artery disease

2.44 (1.94–3.08)

< 0.001

1.65 (1.29–2.11)

< 0.001

 

1.89 (1.38–2.59)

< 0.001

1.96 (1.39–2.74)

< 0.001

Heart failure history

2.14 (1.69–2.70)

< 0.001

1.74 (1.36–2.24)

< 0.001

 

1.94 (1.42–2.65)

< 0.001

1.71 (1.22–2.39)

0.002

Atrial fibrillation

1.29 (1.03–1.62)

0.028

1.22 (0.97–1.55)

0.096

 

1.27 (0.94–1.72)

0.119

1.11 (0.81–1.51)

0.514

Cerebrovascular accident

1.48 (1.12–1.96)

0.006

1.23 (0.93–1.64)

0.154

 

1.17 (0.79–1.74)

0.430

  

Chronic kidney disease

3.19 (2.50–4.08)

< 0.001

1.82 (1.39–2.38)

< 0.001

 

2.05 (1.49–2.81)

< 0.001

1.96 (1.41–2.71)

< 0.001

End-stage renal disease

4.08 (2.92–5.69)

< 0.001

2.37 (1.64–3.43)

< 0.001

 

2.73 (1.63–4.58)

< 0.001

2.29 (1.29–4.07)

0.005

Anemia

3.52 (2.73–4.54)

< 0.001

2.07 (1.58–2.71)

< 0.001

 

2.35 (1.70–3.24)

< 0.001

1.98 (1.43–2.75)

< 0.001

Intravenous temporary pacemaker

1.03 (0.78–1.37))

0.827

   

0.82 (0.56–1.22)

0.326

  

Complex procedure

1.04 (0.81–1.33)

0.763

   

1.11 (0.80–1.52)

0.537

  

Pocket hematoma

0.52 (0.21–1.25)

0.142

   

0.76 (0.28–2.05)

0.587

  

Device-related infection

1.26 (0.59–2.66)

0.553

   

1.32 (0.42–4.16)

0.628

  
  1. The definitions of parameters are the same as Table 1. CI = confidence interval; HR = hazard ratio