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Table 6 Factors associated with significant liver fibrosis

From: Fatty liver is associated with significant liver inflammation and increases the burden of advanced fibrosis in chronic HBV infection

Variables

Univariate

Multivariate

P value

β ± SE

Wald

OR (95% CI)

P value

Age

0.196

    

Gender

0.211

    

HBV DNA (Log10 IU/mL)

0.004

-0.127 ± 0.029

19.317

0.881 (0.832–0.932)

< 0.001

HbeAg (+)

0.706

    

BMI

0.769

    

Hypertension

0.028

0.890 ± 0.341

6.802

2.434 (1.247–4.751)

0.009

T2DM

0.727

    

WBC

0.194

    

PLT

0.086

    

ALB

0.712

    

GLB

0.037

0.040 ± 0.020

3.977

1.041 (1.001–1.083)

0.046

Tbil

0.952

    

ALT

0.002

-0.017 ± 0.005

12.163

0.983 (0.974–0.993)

< 0.001

AST

< 0.001

0.045 ± 0.010

19.461

1.046 (1.025–1.067)

< 0.001

GGT

0.059

0.007 ± 0.003

4.711

1.007 (1.001–1.083)

0.030

ALP

0.952

    

Steatosis

0.784

    
  1. HBV: Hepatitis B virus; HbeAg: hepatitis B e antigen; BMI: Body mass index; T2DM: Type 2 diabetes mellitus; WBC: White blood cell count; PLT: Platelet; ALB: Albumin; GLB: Globulin; Tbil: Total bilirubin; ALT: Alanine aminotransferase; AST: Aspartate transferase; GGT: Gamma-glutamyltransferase; ALP: Alkaline phosphatase
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BMC Infectious Diseases

ISSN: 1471-2334

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