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Table 5 Factors associated with significant liver inflammation

From: Fatty liver is associated with significant liver inflammation and increases the burden of advanced fibrosis in chronic HBV infection

Variables

Univariate

Multivariate

P value

β ± SE

Wald

OR (95% CI)

P value

Age

0.544

    

Gender

0.690

    

HBV DNA (Log10 IU/mL)

0.863

    

HbeAg (+)

0.031

0.436 ± 0.157

7.760

1.547 (1.138–2.103)

0.005

BMI

0.242

    

Hypertension

0.377

    

T2DM

0.756

    

WBC

0.105

    

PLT

0.053

-0.003 ± 0.001

3.644

0.997 (0.994-1.000)

0.056

ALB

0.003

-0.080 ± 0.023

11.827

0.923 (0.881–0.966)

0.001

GLB

0.013

0.057 ± 0.021

7.602

1.059 (1.017–1.103)

0.006

Tbil

0.082

    

ALT

0.038

-0.013 ± 0.005

5.500

0.987 (0.977–0.998)

0.019

AST

< 0.001

0.054 ± 0.012

21.319

1.055 (1.031–1.079)

< 0.001

GGT

0.041

0.008 ± 0.004

4.606

1.008 (1.001–1.015)

0.032

ALP

0.178

    

Steatosis

0.001

0.750 ± 0.176

18.210

2.117 (1.500-2.988)

< 0.001

  1. HBV: Hepatitis B virus; HbeAg: hepatitis B e antigen; BMI: Body mass index; T2DM: Type 2 diabetes mellitus; WBC: White blood cell count; PLT: Platelet; ALB: Albumin; GLB: Globulin; Tbil: Total bilirubin; ALT: Alanine aminotransferase; AST: Aspartate transferase; GGT: Gamma-glutamyltransferase; ALP: Alkaline phosphatase
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BMC Infectious Diseases

ISSN: 1471-2334

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