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Table 1 Clinical characteristics of HBV-infected patients with and without hepatic steatosis

From: Fatty liver is associated with significant liver inflammation and increases the burden of advanced fibrosis in chronic HBV infection

 

HBV infection (N = 616)

HBV infection + NAFLD (N = 255)

P value

Age

38.87 ± 10.19

39.78 ± 9.25

0.222

Gender (M/F)

366/250

220/35

< 0.001

Height

164.63 ± 8.23

167.63 ± 7.97

< 0.001

Weight

60.69 ± 10.14

73.00 ± 10.71

< 0.001

BMI

22.33 ± 2.98

25.98 ± 3.55

< 0.001

WBC

5.61 ± 1.51

6.00 ± 1.37

< 0.001

PLT

184.83 ± 52.47

191.60 ± 52.89

0.084

ALB

43.77 ± 3.57

44.54 ± 3.40

0.003

GLB

29.22 ± 3.93

29.02 ± 4.00

0.482

Tbil

15.23 ± 6.22

16.51 ± 6.29

0.006

ALT

38.62 ± 32.75

52.02 ± 37.48

< 0.001

AST

33.30 ± 19.40

35.81 ± 17.58

0.075

GGT

27.24 ± 26.64

42.89 ± 36.26

< 0.001

ALP

81.10 ± 24.27

89.68 ± 25.51

< 0.001

HBV DNA (Log10 IU/mL)

4.55 ± 2.66

4.23 ± 2.52

0.093

HbeAg (+)

264 (42.86%)

88 (34.51%)

0.022

Anti-viral therapy

36 (5.84%)

17 (6.67%)

0.644

Hypertension

29 (4.71%)

32 (12.55%)

< 0.001

T2DM

7 (1.14%)

13 (5.10%)

< 0.001

  1. NAFLD: Non-alcoholic fatty liver disease; M: Male; F: Female; BMI: Body mass index; WBC: White blood cell count; PLT: Platelet; ALB: Albumin; GLB: Globulin; Tbil: Total bilirubin; ALT: Alanine aminotransferase; AST: Aspartate transferase; GGT: Gamma-glutamyltransferase; ALP: Alkaline phosphatase; HBV: Hepatitis B virus; HbeAg: hepatitis B e antigen; T2DM: Type 2 diabetes mellitus