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Table 1 Characteristics of patients and controls

From: Herpes zoster associated with stroke incidence in people living with human immunodeficiency virus: a nested case–control study

Variable

Cases (stroke)

(n = 509)

n (%)

Controls (non-stroke)

(n = 5,090)

n (%)

p-value

Age (years)

  

0.98

 18–34

80 (15.72)

805 (15.81)

 

 35–44

159 (31.24)

1591 (31.26)

 

 45–54

160 (31.43)

1644 (32.30)

 

 55–64

84 (16.50)

787 (15.46)

 

  ≥ 65

26 (5.11)

263 (5.17)

 

Mean (SD)

46.14 (11.17)

45.73 (11.11)

 

Sex

  

0.53

 Female

46 (9.04)

419 (8.23)

 

 Male

463 (90.96)

4671 (91.77)

 

Geographic area

  

 < 0.001

 North

236 (46.37)

2773 (54.48)

 

 Central

112 (22.00)

985 (19.35)

 

 South

158 (31.04)

1248 (24.52)

 

 East

3 (0.59)

84 (1.65)

 

Monthly income, USD

  

 < 0.001

  < 660.50

333 (65.42)

2368 (46.52)

 

 660.50–1321.00

148 (29.08)

1840 (36.15)

 

  > 1321.04

28 (5.50)

882 ((17.33)

 

Comorbidity

   

 Hypertension

273 (53.63)

1338 (26.29)

 < 0.001

 HCV

230 (45.19)

1597 (31.38)

 < 0.001

 Hyperlipidemia

152 (29.86)

1191 (23.40)

0.001

 HBV

100 (19.65)

897 (17.62)

0.26

 Heart disease

41 (8.06)

122 (2.40)

 < 0.001

 Diabetes mellitus

40 (7.86)

292 (5.74)

0.053

 Chronic kidney disease

33 (6.48)

133 (2.61)

 < 0.001

 Coronary artery disease

15 (2.95)

94 (1.85)

0.087

 Alcohol-related illness

15 (2.95)

78 (1.53)

0.017

 PAOD

5 (0.98)

14 (0.28)

0.009

 AMI

0 (0)

16 (0.31)

-

ART regimen

   

 PIs

116 (22.79)

889 (17.47)

0.003

 NRTIs

88 (17.29)

878 (17.25)

0.98

 NNRTIs

17 (3.73)

123 (2.42)

0.20

  1. SD Standard deviation, USD United States Dollars, HCV Hepatitis C virus, HBV Hepatitis B virus, PAOD Peripheral arterial occlusive disease, AMI Acute myocardial infarction, ART Antiretroviral therapy, PIs Protease inhibitors, NRTIs Nucleoside reverse transcriptase inhibitors, NNRTIs Non-nucleoside reverse transcriptase inhibitors