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Table 2 Comparative analysis of overall mortality by clinical groups and variables of interest

From: Clinical and microbiological characterization of Salmonella spp. isolates from patients treated in a university hospital in South America between 2012–2021: a cohort study

Characteristics

Below 15 years of age

p-value

Above 15 years of age

p-value

Alive, n = 245

Dead, n = 7

Alive. n = 247

Dead, n = 14

Gender

Female

127 (96.5)

4 (3.5)

1.000^

142 (96.0)

6 (4.0)

0.406^

Medical history

 Inflammatory bowel disease

3 (75.0)

1 (25.0)

0.337

3 (75.0)

1 (25.0)

0.199^

 Hematological cancer

15 (100.0)

0

1.000^

38 (88.4)

5 (11.6)

0.061a

 Chronic kidney disease

12 (92.3)

1 (7.7)

0.311^

32 (88.9)

4 (11.1)

0.110^

 Liver disease

7 (100.0)

0

1.000^

18 (90.0)

2 (10.0)

0.292^

 Chemotherapy last three months

15 (100.0)

0

1.000^

33 (91.7)

3 (8.3)

0.419^

 Type 2 diabetes

6 (100.0)

0

1.000^

22 (91.7)

2 (8.3)

0.375^

 Immunosuppressive therapy

33 (97.1)

1 (2.9)

1.000^

66 (94.3)

4 (5.7)

1.000^

Exposure

 Antibiotic use in the last 30 days

38 (100)

0

0.599^

30 (88.2)

4 (11.8)

0.093^

 Foodborne illness

17 (100.0)

0

0.470^

29 (93.5)

2 (6.5)

0.676^

 Travel in the last 3 months

14 (100)

0

1.000^

5 (100)

0

1.000^

Clinical presentation

 Bacteremia

47 (97.9)

1 (2.1)

1.000^

59 (85.8)

10 (14.5)

 < 0.001^

 Gastroenteric syndrome

208 (97.6)

5 (2.4)

0.296^

179 (97.3)

5 (2.7)

0.004a

Characteristics of diarrhea

 Persistent

19 (90.5)

2 (9.5)

0.135^

20 (95.2)

1 (4.8)

1.000^

 Chronic

12 (100)

0

1.000^

14 (100)

0

1.000^

Microbiology

 Resistance to any antibiotic

67 (100)

0

0.581^

46 (92)

4 (8.00)

0.481^

 ESBL

31 (93.9)

2 (6.1)

0.201^

16 (94.1)

1 (5.9)

1.000^

 Positive CNPt

1 (100)

0

1.000^

1 (100)

0

1.000^

 Positive CARBA-5

0

0

 

1 (100)

0

1.000^

Salmonella spp. and salmonella serovars

Salmonella spp.

199 (96.6)

7 (3.4)

 

182 (93.8)

12 (6.2)

 

 NTS

40 (100)

0

 

57 (96.4)

2 (3.6)

0.608^

Salmonella Typhi

6 (100)

0

 

8 (100)

0

 

Outcomes

 ICU

36 (92.3)

3 (7.7)

0.077^

69 (85.2)

12 (14.8)

 < 0.001^

 Hospitalization

189 (97.4)

5 (2.6)

0.663^

197 (93.8)

13 (6.2)

0.316^

  1. NTS Non-typhoideal salmonellae, CNPt CARBA-NP test
  2. a Chi-square test 
  3. ^ Fisher's f-test