Table 4 Adverse reactions reported in the different treatment groups
Variable | Conventional treatment group (N = 130) | Vitamin B6 supplement treatment group (N = 130) | Statistics | P value |
|---|---|---|---|---|
Central nervous system symptoms | 46/130(35.38%) | 41/130(31.54%) | 0.432 | 0.511 |
Mild | 19/46(41.30%) | 35/41(85.37%) | 17.876 | < 0.001 |
Moderate | 15/46(32.61%) | 4/41(9.76%) | 6.632 | 0.010 |
Severe | 12/46(26.09%) | 2/41(4.87%) | 7.222 | 0.007 |
Gastrointestinal symptoms | 6/130(4.62%) | 15/130(11.54%) | 4.200 | 0.041 |
Mild | 4/6(66.67%) | 15/15(100%) | 5.526 | 0.019 |
Moderate | 2/6(33.33%) | 0/15(0.00%) | 5.526 | 0.019 |
Severe | 0/15(0.00%) | 0/15(0.00%) | - | - |
Both central nervous system symptoms and gastrointestinal symptoms | 45/130(34.62%) | 18/130(13.85%) | 15.27 | < 0.001 |
Mild | 16/45(35.56%) | 10/18(55.56%) | 2.122 | 0.145 |
Moderate | 16/45(35.56%) | 4/18(22.22%) | 1.055 | 0.304 |
Severe | 13/45(28.88%) | 4/45(22.22%) | 0.29 | 0.590 |