Table 6 Relation between ZFHX3 (rs2106261) gene polymorphism and laboratory data and prognosis in severe COVID-19 cases (n = 45)

WBCs

4.00–11/(mcL)

Median

11.0

8.70

U = 788.0

0.172

Platelet

150–400/(mcL)

Median

198.0

209.0

U = 936.0

0.894

HB (g/dl)

Male: 14–18 g/dL

Mean ± SD.

Female: 12–16 g/dL

10.79 ± 1.89

10.41 ± 1.85

t = 0.940

0.350

SGOT (U/L)

8–45 (U/L)

Median

36.50

50.0

U = 824.0

0.286

SGPT (U/L)

7–56 (U/L)

Median

27.50

19.0

U = 776.0

0.143

BUN (mg/dL)

6–24 mg/dL

Median

38.0

49.0

U = 820.0

0.272

Creatinine (mg/dL)

Male: 0.6-1.2 mg/dL

Median

Female: 0.5 to 1.1 mg/dL

1.04

1.50

U = 682.0^*

0.024^*

Na⁺(mEq/L)

135–145 (mEq/L)

Mean ± SD.

139.98 ± 3.82

140.53 ± 7.45

t = 0.463

0.645

 K⁺(mEq/L)

3.5–5.3 (mEq/L

Mean ± SD.

4.38 ± 0.69

4.57 ± 0.72

t = 1.295

0.199

TG (mg/dL)

Male: 40–160 mg/dL

Median

Female: 35–135 mg/dL

130.0

130.0

U = 932.0

0.868

Cholesterol (mg/dL)

125–200 mg/dL

Median

126.0

107.50

U = 724.0

0.0577

HDL (mg/dL)

Male: 35–55 mg/dL

Median

Female: 45–65 mg/dL

35.0

35.0

U = 902.0

0.677

LDL (mg/dL)

< 130 mg/dL

Median

53.95

40.60

U = 660.0^*

0.015^*

PC%

Mean ± SD.

73.24 ± 19.25

73.38 ± 15.67

t = 0.037

0.970

INR

0.9–1.1

Median

1.15

1.20

U = 900.0

0.664

CRP (mg/L)

< 3 mg/L

Median

54.50

78.0

U = 856.0

0.423

Ferritin (µg/L)

Male: 24–336 (µg/L)

Median

Female: 11–307 (µg/L)

447.50

440.0

U = 880.0

0.549

D-dimer (µg/mL)

0-0.50 (µg/mL)

Median

1.04

0.90

U = 952.0

1.000

Prognosis

Improved

22 (39.3%)

6 (17.6%)

χ²=4.622^*

0.032^*

Death

34 (60.7%)

28 (82.4%)