Table 4 Relation between CDKN2B-AS1 (rs1333049) gene polymorphism and laboratory data and prognosis in severe COVID-19 cases (n = 90)

WBCs

4.00–11/(mcL)

Median

25.50

10.50

7.40

 H = 15.890^*

< 0.001^*

Platelet

150–400/(mcL)

Median

298.0

190.0

219.0

 H = 21.249^*

< 0.001^*

HB (g/dl)

Male: 14–18 g/dL

Mean ± SD.

Female: 12–16 g/dL

10.03 ± 1.33

10.77 ± 1.93

10.60 ± 2.22

 F = 0.779

0.462

SGOT (U/L)

8–45 (U/L)

Median

42.0

37.0

37.0

 H = 0.811

0.667

SGPT (U/L)

7–56 (U/L)

Median

27.50

26.50

17.0

 H = 1.792

0.408

BUN (mg/dL)

6–24 mg/dL

Median

42.0

47.50

49.0

 H = 0.451

0.798

Creatinine (mg/dL)

Male: 0.6-1.2 mg/dL

Median

Female: 0.5 to 1.1 mg/dL

1.35

1.28

1.60

 H = 0.083

0.959

Na⁺(mEq/L)

135–145 (mEq/L)

Mean ± SD.

141.50 ± 4.76

139.84 ± 5.79

140.63 ± 5.02

 F = 0.516

0.599

 K⁺(mEq/L)

3.5–5.3 (mEq/L)

Mean ± SD.

4.47 ± 0.75

4.41 ± 0.72

4.61 ± 0.63

 F = 0.495

0.611

TG (mg/dL)

Male: 40–160 mg/dL

Median

Female: 35–135 mg/dL

144.50

130.0

114.0

 H = 4.067

0.131

Cholesterol (mg/dL)

125–200 mg/dL

Median

122.50

116.0

107.50

 H = 0.325

0.850

HDL (mg/dL)

Male: 35–55 mg/dL

Median

Female: 45–65 mg/dL

41.25

35.50

28.50

 H = 7.224^*

0.02^*7

LDL (mg/dL)

< 130 mg/dL

Median

48.50

46.30

48.92

 H = 0.435

0.805

PC%

Mean ± SD.

72.85 ± 19.02

73.71 ± 18.47

71.76 ± 15.15

 F = 0.071

0.931

INR

0.9–1.1

Median

1.25

1.18

1.20

 H = 1.838

0.399

CRP (mg/L)

< 3 mg/L

Median

48

54.5

78.0

 H = 1.599

0.450

Ferritin (µg/L)

Male: 24–336 (µg/L)

Median

Female: 11–307 (µg/L)

225.0

538.50

380.0

 H = 17.033^*

< 0.001^*

D-dimer (µg/mL)

0-0.50 (µg/mL)

Median

0.99

1.04

0.70

 H = 8.32^*2

0.0^*16

Prognosis

Improved

2 (16.7%)

22 (34.4%)

4 (28.6%)

χ²=1.529

0.466

Death

10 (83.3%)

42 (65.6%)

10 (71.4%)