Table 3 Detection of TB genotypes at baseline and follow-up among the study participants
Lineage | Lineage distribution n (%) | Genotype | Region | TOTAL | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Hhohho n(%) | Manzini n(%) | Lubombo n(%) | Shiselweni n/13(%) | n(%) | |||||||
Baseline | Follow-up | Baseline | Follow-up | Baseline | Follow-up | Baseline | Follow-up | ||||
Indo-Oceanic (Lineage 1) | 20 (9.71) | EAI6-BGD1 | 1 (4.76) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (7.69) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 2 (0.97) |
EAI1-SOM | 2 (9.52) | 0 (0.00) | 8 (14.29) | 3 (5.36)) | 1 (7.69) | 0 (0.00) | 1 (7.69) | 0 (0.00) | 15 (7.28) | ||
Manu1 | 1 (4.76) | 1 (4.76) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 2 (0.97) | ||
Manu2 | 0 (0.00) | 1 (4.76) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (0.49) | ||
East Asian (Lineage 2) | 50 (24.27) | BEIJING | 2 (9.52) | 8 (38.10) | 4 (7.14) | 25 (44.64) | 2 (15.39) | 6 (46.15) | 1 (7.69) | 2 (15.39) | 50 (24.27) |
Central Asian (Lineage 3) | 4 (1.94) | CAS1-Delhi | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (7.69) | 1 (0.49) |
CAS1-Kili | 1 (4.76) | 0 (0.00) | 1 (1.79) | 0 (0.00) | 0 (0.00) | 1 (7.69) | 0 (0.00) | 0 (0.00) | 3 (1.46) | ||
Euro-American (Lineage 4) | 95 (46.12) | X2 | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (7.69) | 0 (0.00) | 1 (0.49) |
X3 | 3 (14.29) | 1 (4.76) | 4 (7.14) | 3 (5.36) | 1 (7.69) | 1 (7.69) | 1 (7.69) | 1 (7.69) | 14 (6.80) | ||
LAM1 | 0 (0.00) | 1 (4.76) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 2 (15.39) | 0 (0.00) | 0 (0.00) | 1 (0.49) | ||
LAM3 | 1 (4.76) | 0 (0.00) | 3 (5.36) | 0 (0.00) | 2 (15.39) | 3 (23.08) | 0 (0.00) | 1 (7.69) | 7 (3.40) | ||
LAM4 | 0 (0.00) | 1 (4.76) | 3 (5.36) | 4 (7.14) | 0 (0.00) | 4 (30.77) | 2 (15.39) | 0 (0.00) | 10 (4.85) | ||
LAM5 | 0 (0.00) | 0 (0.00) | 1 (1.79) | 0 (0.00) | 0 (0.00) | 1 (7.69) | 0 (0.00) | 0 (0.00) | 2 (0.97) | ||
LAM9 | 1 (4.76) | 0 (0.00) | 1 (1.79) | 0 (0.00) | 0 (0.00) | 1 (7.69) | 0 (0.00) | 0 (0.00) | 3 (1.46) | ||
LAM-RUS | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (1.79) | 1 (7.69)) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 2 (0.97) | ||
LAM11-ZWE | 1 (4.76) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (7.69) | 2 (0.97) | ||
S | 5 (23.81) | 3 (14.29) | 9 (16.07) | 3 (5.36) | 3 (23.08) | 3 (23.08) | 3 (23.08) | 5 (38.46) | 34 (16.50) | ||
T1 | 0 (0.00) | 3 (0.14) | 7 (12.50) | 5 (8.93) | 1 (7.69) | 0 (0.00) | 0 (0.00) | 1 (7.69) | 17 (8.25) | ||
T2 | 0 (0.00) | 0 (0.00) | 1 (1.79) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (0.49) | ||
T-H37Rv | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (1.79) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (0.49) | ||
Orphan | 37 (17.96) | Orphan | 3 (0.14) | 2 (0.1) | 14 (25.00) | 11 (19.64) | 1 (7.69) | 1 (7.69) | 4 (30.77) | 1 (7.69) | 37 (17.96) |
TOTAL | 21 (10.19%) | 21 (10.19%) | 56 (27.18%) | 56 (27.18%) | 13 (6.31%) | 13 (6.31%) | 13 (6.31%) | 13 (6.31%) | 206 (100) | ||