Skip to main content

Table 2 The table shows DST pattern for all the first line drugs used in Eswatini per region

From: Molecular investigations of Mycobacterium tuberculosis genotypes among baseline and follow-up strains circulating in four regions of Eswatini

TB drugs

DST

Region

p-value

Baseline

n (%)

Follow up

n (%)

Total

n (%)

p-value

Hhohho

n (%)

Manzini

n (%)

Lubombo n (%)

Shiselweni n (%)

Total

n (%)

RIF

S

25 (59.5)

69 (61.6)

13 (50)

18 (69.2)

125 (60.7)

0.557

72 (69.9)

53 (51.5)

125 (60.7)

0.005*

R

17 (40.5)

43 (38.4)

13 (50)

8 (30.8)

81 (39.3)

31 (30.1)

50 (48.5)

81 (39.3)

Total

42 (100)

112 (100)

26 (100)

26 (100)

206 (100)

103 (100)

103 (100)

206 (100)

INH

S

31 (73.8)

82 (73.2)

15 (57.7)

22 (84.6)

150 (72.8)

0.197

80 (77.7)

70 (68.0)

150 (72.8)

0.079

R

11 (26.2)

30 (26.8)

11 (42.3)

4 (15.4)

56 (27.2)

23 (22.3)

33 (32.0)

56 (27.2)

Total

42 (100)

112 (100)

26 (100)

26 (100)

206 (100)

103 (100)

103 (100)

206 (100)

STR

S

28 (66.7)

74 (66.1)

16 (61.5)

19 (73.1)

137 (66.5)

0.853

75 (72.8)

62 (60.2)

137 (66.5)

0.038*

R

14 (33.3)

38 (33.9)

10 (38.5)

7 (26.9)

69 (33.5)

28 (27.2)

41 (39.8)

69 (33.5)

Total

42 (100)

112 (100)

26 (100)

26 (100)

206 (100)

103 (100)

103 (100)

206 (100)

EMB

S

29 (69)

79 (70.5)

17 (65.4)

21 (80.8)

146 (70.9)

0.639

81 (78.6)

65 (63.1)

146 (70.9)

0.011*

R

13 (31)

33 (29.5)

9 (34.6)

5 (19.2)

60 (29.1)

22 (21.4)

38 (36.9)

60 (29.1)

Total

42 (100)

112 (100)

26 (100)

26 (100)

206 (100)

81 (78.6)

65 (63.1)

146 (70.9)

  1. RIF Rifampicin, INH Isoniazid, STR Streptomycin, EMB Ethambutol, S Susceptible, R Resistant
  2. *p-value significant at p < 0.05