Prevalence of gram-negative bacteria and their antibiotic resistance in neonatal sepsis in Iran: a systematic review and meta-analysis

Table 4 Subgroup analysis for the antibiotic resistance pattern among two more prevalent gram-negative bacteria

Bactria	Antibiotic	Studies (n)	Heterogeneity		95%CI	Pooled prevalence (%)	Model
Bactria	Antibiotic	Studies (n)	I²	P-Value	95%CI	Pooled prevalence (%)	Model
K.pneumoniae	Amikacin	22	91.391	< 0.001	0.404–0.645	0.526	Random
	Ampicillin	15	95.984	< 0.001	0.467–0.761	0.625	Random
	Cefixime	5	76.380	0.002	0.562–0.932	0.807	Random
	Cefotaxime	17	96.371	< 0.001	0.490–0.758	0.634	Random
	Ceftazidime	8	92.319	< 0.001	0.547–0.874	0.744	Random
	Ceftizoxime	8	92.487	< 0.001	0.423–0.816	0.643	Random
	Ceftriaxone	13	84.418	< 0.001	0.481–0.774	0.640	Random
	Cephalothin	8	94.824	< 0.001	0.522–0.868	0.728	Random
	Ciprofloxacin	15	92.242	< 0.001	0.296–0.592	0.439	Random
	Cotrimoxazole	13	92.790	< 0.001	0.292–0.600	0.440	Random
	Gentamicin	24	91.059	< 0.001	0.513–0.735	0.613	Random
	Imipenem	10	97.304	< 0.001	0.258–0.634	0.454	Random
Overall			94.856	< 0.001	0.521–0.675	0.600	Random
E.Coli	Amikacin	17	95.123	< 0.001	0.332–0.567	0.441	Random
	Ampicillin	10	97.262	< 0.001	0.443–0.765	0.617	Random
	Cefixime	8	78.180	< 0.001	0.377–0.750	0.574	Random
	Cefotaxime	13	94.598	< 0.001	0.358–0.635	0.496	Random
	Ceftazidime	9	92.769	< 0.001	0.315–0.652	0.481	Random
	Ceftizoxime	5	83.306	< 0.001	0.232–0.655	0.431	Random
	Ceftriaxone	6	83.897	< 0.001	0.321–0.730	0.531	Random
	Cephalothin	5	85.061	< 0.001	0.289–0.737	0.517	Random
	Ciprofloxacin	15	91.268	< 0.001	0.316–0.575	0.441	Random
	Cotrimoxazole	14	94.255	< 0.001	0.293–0.557	0.419	Random
	Gentamicin	19	91.375	< 0.001	0.280–0.511	0.389	Random
	Imipenem	10	97.744	< 0.001	0.227–0.527	0.364	Random
Overall			96.213	< 0.001	0.405–0.527	0.466	Random

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