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Table 1 Cohort demographics and clinical information

From: The metabolic consequences of HIV/TB co-infection

 

HIV-/TB-/Tn-

HIV-/TB + /Tn-

HIV + /TB + /Tn-

HIV + /TB + /Tn + 

No. of patients (%)

29 (40.3)

22 (30.6)

9 (12.5)

12 (16.7)

Age (years), mean ± SD (range)

33.4 ± 10.3

34.4 ± 12.8

31.9 ± 6.2

40.9 ± 10.6

Sex, male: female ratio (%)

13:16 (45:55)

13:9 (59:41)

5:4 (56:44)

4:8 (33:67)

Smokers in the group (%)

9 (31.0)

11 (50.0)

2 (22.2)

3 (25.0)

CD4 T-cell count (cells/mm3 blood), mean ± SD, before exclusion

N/A

N/A

221.4 ± 252.4

182.7 ± 162.2

Viral load (copies/mm3), range a

N/A

N/A

 < 20–124

 < detectable–513 509

Duration of ART (years), mean ± SD

N/A

N/A

N/A

4.3 ± 3.6

Patients on FDC ART combination (%)

N/A

N/A

N/A

10 (83.3)

Patients on different ART combinations (%)

N/A

N/A

N/A

2 (16.7)

No. of patients (%), after exclusion

24 (36.9)

22 (33.8)

7 (10.8)

12 (18.5)

Age (years), mean ± SD (range)

34.0 ± 10.3

34.4 ± 12.8

32.3 ± 5.1

40.9 ± 10.6

Sex, male: female ratio (%)

11:13 (54:46)

13:9 (59:41)

4:3 (57:43)

4:8 (33:67)

Smokers in the group (%)

8 (33.3)

11 (50.0)

2 (28.5)

3 (25.0)

CD4 T-cell count (cells/mm3 blood), mean ± SD, after exclusion

N/A

N/A

78.29 ± 87.44

182.7 ± 162.2

  1. ART antiretroviral therapy, SD standard deviation, FDC fixed-dose combination
  2. Groups: HIV-/TB-/Tn-: healthy controls; HIV-/TB + /Tn-: untreated HIV-negative patients with active pulmonary TB; HIV + /TB + /Tn-: untreated HIV/TB co-infected patients; HIV + /TB + /Tn + : HIV/TB co-infected patients on ART
  3. a Viral load was not available for all patients, hence the data shown here are not representative of the entire group. CD4 T-cell counts, and viral load also varied due to differences in ART duration